Table 3 Clinical characteristics of 7 children who received neoadjuvant chemotherapy
From: Pediatric adrenocortical carcinoma: clinical features and application of neoadjuvant chemotherapy
Number | Age (m) | Stage | Maximum tumor size before neoadjuvant chemotherapy (cm) | Maximum tumor size after neoadjuvant chemotherapy (cm) | Change in maximum diameter (cm) | RECIST | Volume before neoadjuvant chemotherapy (ml) | Volume after neoadjuvant chemotherapy (ml) | Change in volume (ml) | Percent reduction in volume (%) | Reasons for neoadjuvant chemotherapy | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 77 | IV | 8.5 | 8.6 |  + 0.1 | SD | – | – | – | – | Intravenous tumor thrombus and distant metastasis | Death |
2 | 36 | IV | 13.5 | 10.5 | − 2.0 | SD | 868.4 | 575.0 | − 293.4 | 33.8 | Maximum diameter greater than 10 cm and intravenous tumor thrombus | Death |
3 | 113 | II | 10.6 | 8 | − 2.6 | SD | 619.0 | 206.5 | − 412.5 | 66.6 | Maximum diameter greater than 10 cm | Alive |
4 | 4 | IV | 7.0 | 3.6 | − 3.4 | PR | 55.7 | 6.6 | − 49.1 | 88.2 | Distant metastasis | Alive |
5 | 43 | III | 11.5 | 6.7 | − 4.8 | PR | 365.5 | 94.9 | − 270.6 | 74.0 | Maximum diameter greater than 10 cm | Alive |
6 | 59 | III | 15 | 13.6 | − 1.4 | SD | – | – | – | – | Maximum diameter greater than 10 cm and invasion of surrounding tissues | Death |
7 | 12 | III | 8 | 7 | − 1.0 | SD | 199.0 | 116.0 | − 83.0 | 41.7 | Invasion of surrounding tissues | Alive |