Table 3 Comparison of cytokine levels between AE-CTD-ILD and S-CTD-ILD
Variables | S-CTD-ILD (n = 32), pg/mL | AE-CTD-ILD (n = 29), pg/mL | P value |
|---|---|---|---|
IL-2 | 0.9 (0.6–1.3) | 1.0 (0.7–2.4) | 0.233 |
IL-4 | 1.4 (0.9–2.7) | 1.8 (1.1–3.0) | 0.583 |
IL-5 | 0.8 (0.3–1.2) | 0.9 (0.4–1.5) | 0.435 |
IL-6 | 5.6 (3.6–18.6) | 53.2 (18.6–118.3) | < 0.001*** |
IL-8 | 56.9 (8.4–260.1) | 402.9 (184.1–827.1) | < 0.001*** |
IL-10 | 4.5 (2.6–5.4) | 5.7 (3.5–8.1) | 0.070 |
IL-1β | 5.2 (1.7–10.0) | 8.6 (2.8–15.1) | 0.147 |
IL-17A | 9.4 (5.2–13.1) | 13.0 (5.1–20.3) | 0.220 |
IL-12p70 | 2.8 (1.4–5.1) | 3.4 (1.8–4.5) | 0.908 |
TNF-α | 2.31 (0.88–6.82) | 6.0 (3.6–20.1) | 0.022* |
IFN-α | 2.1 (1.6–3.8) | 2.9 (1.7–5.0) | 0.201 |
IFN-γ | 2.5 (1.5–5.0) | 2.4 (2.0–4.6) | 0.288 |