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Table 4 Univariate and multivariable analyses of survival factors in patients with HCC

From: Overexpression of TMEM79 combined with SMG5 is related to prognosis, tumor immune infiltration and drug sensitivity in hepatocellular carcinoma

 

Univariate analysis

Multivariate analysis

HR

P >|z|

95% CI

HR

P >|z|

95% CI

TMEM79 expression

        

 High vs low or none

4.552

 < 0.001a

3.047

6.801

3.833

 < 0.001a

2.520

5.831

SMG5 expression

        

 High vs low or none

2.945

 < 0.001a

1.984

4.372

1.903

0.002a

1.257

2.883

Age (years)

        

  ≤ 60 vs > 60

1.001

0.995

0.694

1.444

    

Gender

        

 Male vs female

1.183

0.373

0.818

1.712

    

Tumor diameter (cm)

        

  ≤ 3 vs > 3

1.482

0.015a

1.079

2.037

1.446

0.039a

1.019

2.051

AFP (μg/L)

        

  ≤ 400 vs > 400

1.091

0.644

0.754

1.579

    

Tumor number

        

 Solitary vs multiple

0.491

0.001a

0.328

0.737

0.976

0.927

0.578

1.647

TNM stage

        

 I vs II vs III + IV

1.878

 < 0.001a

1.612

2.187

1.487

0.119

0.904

2.446

T

        

 1 vs 2 vs 3 vs 4

2.274

< 0.001a

1.839

2.813

1.338

0.179

0.875

2.044

N

        

 0 vs 1

2.005

0.126

0.822

4.895

    

M

        

 0 vs 1

4.278

< 0.001a

2.590

7.066

0.910

0.852

0.338

2.451

Differentiation

        

 Well vs moderate vs poor

1.211

0.146

0.936

1.566

    

Hepatitis B virus infection

        

 No vs yes

0.762

0.384

0.412

1.406

    

Vascular invasion

        

 No vs yes

1.763

0.003a

1.209

2.571

0.351

0.318

0.045

2.734

Liver Cirrhosis

        

 No vs yes

0.945

0.723

0.689

1.294

    

Recurrence

        

 No vs yes

1.812

0.002a

1.247

2.633

1.968

0.508

0.265

14.638

  1. HCC hepatocellular carcinoma, HR hazard ratio, CI confidence interval
  2. aP < 0.05 was considered significant
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European Journal of Medical Research

ISSN: 2047-783X

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