Table 3 Clinical characteristics of PNM patients received AP or not
From: Effect of antibiotic prophylaxis in the prognosis of Post-neurosurgical meningitis patients
Characteristics | AP (929) | Non-AP (261) | Total (1190) | P |
|---|---|---|---|---|
Age | 41 (27, 54) | 42 (27,54) | 42 (27, 54) | 0.846 |
Gender | 524 (56.4%) | 154 (59.0%) | 679 (57.0%) | 0.48 |
Diabetes | 44 (4.7%) | 15 (5.7%) | 59 (5.0%) | 0.519 |
Hypertension | 146 (15.7%) | 49 (18.8%) | 195 (16.4%) | 0.256 |
Tumour | 663 (71.4%) | 183 (70.1%) | 846 (71.1%) | 0.7 |
Glioma | 230 (24.8%) | 62 (23.8%) | 292 (24.5%) | |
Meningioma | 138 (14.9%) | 56 (21.5%) | 194 (16.3%) | |
Pituitary tumor/craniopharyngioma | 158 (17.0%) | 31 (11.9%) | 189 (15.9%) | |
Others | 137 (14.7%) | 34 (13.0%) | 171 (14.4%) | |
Malignant tumor | 290 (31.2%) | 84 (32.2%) | 374 (31.4%) | 0.763 |
Traumatic brain injury | 36 (3.9%) | 21 (8.0%) | 57 (4.8%) | 0.008 |
Operation duration | 4.2 (3.0, 6.0) | 3.5 (2.0, 6.0) | 4.0 (2.8, 6.0) | 0.001 |
Reoperation | 186 (20.0%) | 69 (26.4%) | 255 (21.4%) | 0.013 |
Craniotomy | 664 (71.5%) | 161 (61.7%) | 825 (69.3%) | 0.003 |
Type I incision | 478 (51.5%) | 124 (47.5%) | 602 (50.6%) | 0.263 |
ICU admission | 378 (40.7%) | 111 (42.5%) | 489 (41.1%) | 0.618 |
CSF Leakage | 129 (13.9%) | 44 (16.9%) | 173 (14.5%) | 0.234 |
EVD(external ventricular drainage) | 311 (33.5%) | 103 (39.5%) | 414 (34.8%) | 0.078 |
LD(lumbar drainage) | 250 (26.9%) | 79 (30.3%) | 329 (27.6%) | 0.309 |
AMV(assisted mechanical ventilator) | 384 (41.3%) | 102 (39.1%) | 486 (40.8%) | 0.522 |
Body temperature | 37.7 ± 0.9 | 37.6 ± 0.9 | 37.7 ± 0.9 | 0.807 |
Coma | 49 (5.3%) | 57 (21.8%) | 106 (8.9%) | < 0.001 |
Length of hospitalize | 22.0 (16.0, 34.0) | 23.0 (16.0, 32.0) | 22.0 (16.0. 34.0) | 0.576 |
Cure time | 5.0 (2.0, 11.0) | 5.0 (3.0, 12.0) | 5.0 (2.0, 11.0) | 0.651 |
Postoperative infection time | 7.0 (4.0, 12.0) | 7.0 (4.0, 13.0) | 7.0 (4.0, 12.0) | 0.983 |
Fee | 71010.0 (50315.8, 119021.2) | 79160.5 (50704.7, 142460.0) | 72259.0 (50413.0, 123340.5) | 0.117 |
All-cause mortality | 110 (11.8%) | 61 (23.4%) | 171 (14.4%) | < 0.001 |