Table 5 Univariate and multvariate analysis of clinical characteristics of AP patients
From: Effect of antibiotic prophylaxis in the prognosis of Post-neurosurgical meningitis patients
Characteristics | Univariate analysis | Multivariate regression analysis | ||||
|---|---|---|---|---|---|---|
Survivors (819) | Non-survivors (110) | P | OR | 95%C.I | P | |
Age | 41 (27, 54) | 46 (28, 58) | ||||
Gender | 454 (55.4%) | 72 (65.5%) | ||||
Tumor | 581 (70.9%) | 82 (74.5%) | 0.443 | |||
Malignant tumor | 250 (30.5%) | 40 (36.4%) | 0.200 | |||
Traumatic brain injury | 26 (3.2%) | 10 (9.1%) | < 0.001 | 2.508 | 0.563–11.169 | 0.228 |
Diabetes | 36 (4.4%) | 8 (7.3%) | 0.175 | |||
Hypertension | 115 (14.0%) | 31 (28.2%) | < 0.001 | 1.329 | 0.509–3.471 | 0.561 |
Operation duration | 4.0 (3.0, 6.0) | 5.0 (3.4, 7.5) | 0.008 | 1.120 | 0.963–1.304 | 0.142 |
Reoperation | 143 (17.5%) | 43 (39.1%) | < 0.001 | 1.516 | 0.626–3.668 | 0.356 |
Craniotomy | 581 (70.9%) | 83 (75.5%) | 0.212 | |||
Type I incision | 421 (51.4%) | 57 (51.8%) | 0.970 | |||
ICU admission | 293 (35.8%) | 85 (77.3%) | < 0.001 | 14.337 | 1.716–119.798 | 0.014 |
CSF leakage | 108 (13.2%) | 21 (19.1%) | 0.095 | |||
EVD( external ventricular drainage) | 257 (31.4%) | 54 (49.1%) | < 0.001 | 1.093 | 0.452–2.643 | 0.843 |
LD(lumbar drainage) | 203 (24.8%) | 47 (42.7%) | < 0.001 | 0.875 | 0.0369–2.076 | 0.763 |
AMV(assisted mechanical ventilator) | 299 (36.5%) | 85 (77.3%) | < 0.001 | 2.841 | 1.078–7.492 | 0.035 |
Body temperature | 37.6 ± 0.9 | 37.8 ± 1.0 | 0.017 | 1.287 | 0.599–1.323 | 0.565 |
Coma | 34 (4.2%) | 37 (33.6%) | < 0.001 | 2.306 | 0.959–5.544 | 0.062 |
Length of hospitalize | 21 (16, 32) | 31 (18, 46) | 0.840 | |||
Cure time | 5 (2, 10) | 7 (3, 17) | < 0.001 | 1.004 | 0.973–1.037 | 0.792 |