Table 5 Univariable Cox regression analysis of factors associated with survival of patients

Age (years)

 ≥ 60 vs. < 60

0.982 (0.510–1.894)

1.021 (0.533–1.957)

Gender

 Female vs. male

1.184 (0.625–2.245)

1.118 (0.590–2.116)

Pre-therapy tumor size (cm)

 ≥ 5 vs. < 5

1.850 (1.121–3.055)

1.998 (1.048–3.809)

Tumor location

 Gastric vs. GEJ

1.085 (0.555–2.119)

1.388 (0.713–2.702)

Extent of resection

 Subtotal vs. total

1.216 (0.630–2.347)

1.682 (0.867–3.262)

Clinical T stage

 T3/4a/4b vs. T2

1.614 (0.847–3.076)

1.431 (0.724–2.827)

Clinical N stage

 N-positive vs. N-negative

1.309 (0.681–2.515)

1.690 (0.795–3.591)

Clinical TNM stage

 III/IVA vs. IIA/IIB

1.931 (1.007–3.700)

2.329 (1.107–4.899)

NAC

 Yes vs. no

0.437 (0.231–0.828)

0.382 (0.182–0.800)

Lauren type

 Intestinal vs. diffuse/mixed

0.884 (0.456–1.715)

0.6721 (0.469–1.073)

Histological grade

 Poorly vs. well/moderate

1.687 (0.856–3.726)

2.306 (1.090–4.878)

Signet ring cell

 Yes vs. no

1.461 (0.826–2.341)

1.304 (0.724–2.431)

Pathological T stage

 T3/4a/4b vs. T0/1/2

2.384 (1.219–4.661)

2.277 (1.028–5.040)

Pathological N stage

 N-positive vs. N-negative

1.944 (0.994–3.800)

2.049 (1.005–4.174)

Lymphovascular invasion

 Yes vs. no

2.153 (1.123–4.128)

2.600 (1.289–5.242)

Pathological TNM stage

 III/IV vs. 0/I/II

3.487 (1.810–6.717)

3.413 (1.723–6.761)