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Table 2 Univariate Cox analysis of risk factors for death within 28 days in patients

From: Association between ferritin to albumin ratio and 28-day mortality in patients with sepsis: a retrospective cohort study

Variables

Univariable COX

HR

95% CI

P

Age (years)

0.998

0.9926,1.0035

0.483

Gender (%)

   

 Female

Ref.

  

 Male

1.0048

0.8528,1.1838

0.955

 Length of stay in hospital

0.9962

0.9958,0.9967

 < 0.001

 Length of stay in ICU

0.9986

0.9982,0.999

 < 0.001

Vital signs

   

 HR (beats/min)

1.0036

1,1.0071

0.048

 SBP (mmHg)

0.996

0.9927,0.9994

0.021

 DBP (mmHg)

0.9949

0.9903,0.9995

0.029

 MAP (mmHg)

0.994

0.9896,0.9984

0.008

 RR (t/min)

1.02

1,1.03

0.015

 SpO2 (%)

0.98

0.96,0.99

0.002

 Temperature (℃)

0.93

0.86,1

0.064

 ALB (g/dL)

0.79

0.7,0.9

 < 0.001

 Ferritin (ng/mL) (Log2)

1.17

1.13,1.22

 < 0.001

 FAR (Log2)

1.17

1.13,1.22

 < 0.001

 AG (mg/dL)

1.04

1.02,1.05

 < 0.001

 Bicarbonate (mg/dL)

0.98

0.96,0.99

 < 0.001

 Calcium (mg/dL)

0.98

0.92,1.05

0.616

 Chloride, mean ± SD

0.99

0.98,1

0.038

 Sodium (mEq/L)

1.0003

0.9894,1.0113

0.959

 Potassium (mEq/L)

1.03

0.96,1.12

0.396

 HCT (%)

0.9954

0.984,1.007

0.438

 HGB (g/dL)

0.99

0.95,1.02

0.471

 RBC (109/L)

0.91

0.83,1

0.059

 RDW (%)

1.04

1.01,1.07

0.004

 Glu (mg/dL)

1

1,1

 < 0.001

 BUN (mg/dL)

1.0032

1.0009,1.0055

0.006

 Crea (mg/dL)

1.0008

0.9643,1.0387

0.968

 PLT (109/L)

0.999

0.9984,0.9996

0.002

 WBC (109/L)

1.0073

1.0024,1.0122

0.003

Comorbidities, n(%)

   

 Myocardial infarct

   

 No

Ref.

  

 Yes

1.11

0.91,1.36

0.311

 Congestive heart failure

   

 No

Ref.

  

 Yes

0.97

0.82,1.15

0.719

Chronic pulmonary disease

   

 No

Ref.

  

 Yes

1.13

0.95,1.34

0.169

Diabetes

   

 No

Ref.

  

 Yes

0.53

0.4,0.7

 < 0.001

Renal disease

   

 No

Ref.

  

 Yes

0.76

0.63,0.91

0.002

Malignant cancer

   

 No

Ref.

  

 Yes

0.91

0.74,1.13

0.39

Severe liver disease

   

 No

Ref.

  

 Yes

1.51

1.23,1.84

 < 0.001

Metastatic solid tumor

   

 No

Ref.

  

 Yes

1.6

1.25,2.03

 < 0.001

 Sofa score

1.1

1.07,1.13

 < 0.001

  1. HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, RR respiratory rate, SpO2 oxygen saturation, ALB albumin, FAR ferritin/albumin ratio, AG anion gap, HCT hematocrit, HGB hemoglobin, RBC red blood cells, RDW erythrocyte distribution width, Glu glucose, BUN blood urea nitrogen, Crea creatinine, PLT platelets, WBC white blood cell