Table 1 Baseline characteristics of all patients, and of patients grouped by survival outcome
Overall (n = 955) | Survival (n = 497) | Death (n = 458) | p | |
|---|---|---|---|---|
Demographic | ||||
Female, n (%) | 395 (41.4) | 187 (37.6) | 208 (45.4) | 0.018 |
Age, y(median [IQR]) | 66.00 [55.00, 77.00] | 64.00 [54.00, 75.00] | 69.00 [56.00, 79.00] | < 0.001 |
BMI, kg/m2(median [IQR]) | 27.21 [23.26, 32.32] | 27.87 [24.18, 32.65] | 26.67 [22.69, 31.89] | 0.012 |
Diagnosis [underlying cardiac causes], n (%) | 74 (7.7) | 55 (11.1) | 19 (4.1) | < 0.001 |
Admission location [Emergency], n (%) | 541 (56.6) | 270 (54.3) | 271 (59.2) | 0.149 |
Comorbidities | ||||
aCCI, median [IQR] | 6.00 [4.00, 9.00] | 6.00 [4.00, 8.00] | 7.00 [5.00, 9.00] | < 0.001 |
Age_score, median [IQR] | 3.00 [2.00, 4.00] | 3.00 [2.00, 4.00] | 4.00 [2.00, 4.00] | < 0.001 |
Myocardial_infarct, n (%) | 264 (27.6) | 151 (30.4) | 113 (24.7) | 0.058 |
Congestive_heart_failure, n (%) | 424 (44.4) | 234 (47.1) | 190 (41.5) | 0.094 |
Peripheral_vascular_disease, n (%) | 137 (14.3) | 64 (12.9) | 73 (15.9) | 0.209 |
Cerebrovascular_disease, n (%) | 135 (14.1) | 58 (11.7) | 77 (16.8) | 0.029 |
Dementia, n (%) | 38 (4.0) | 18 (3.6) | 20 (4.4) | 0.672 |
Chronic_pulmonary_disease, n (%) | 241 (25.2) | 129 (26.0) | 112 (24.5) | 0.646 |
Rheumatic_disease, n (%) | 35 (3.7) | 16 (3.2) | 19 (4.1) | 0.554 |
Peptic_ulcer_disease, n (%) | 34 (3.6) | 21 (4.2) | 13 (2.8) | 0.327 |
Mild_liver_disease, n (%) | 169 (17.7) | 78 (15.7) | 91 (19.9) | 0.109 |
Diabetes_without_cc, n (%) | 282 (29.5) | 136 (27.4) | 146 (31.9) | 0.145 |
Diabetes_with_cc, n (%) | 160 (16.8) | 92 (18.5) | 68 (14.8) | 0.153 |
Paraplegia, n (%) | 34 (3.6) | 19 (3.8) | 15 (3.3) | 0.778 |
Renal_disease, n (%) | 335 (35.1) | 175 (35.2) | 160 (34.9) | 0.983 |
Malignant_cancer, n (%) | 124 (13.0) | 45 (9.1) | 79 (17.2) | < 0.001 |
Severe_liver_disease, n (%) | 52 (5.4) | 18 (3.6) | 34 (7.4) | 0.015 |
Metastatic_solid_tumor, n (%) | 52 (5.4) | 11 (2.2) | 41 (9.0) | < 0.001 |
AIDS, n (%) | 7 (0.7) | 2 (0.4) | 5 (1.1) | 0.27 |
SEPSIS, n (%) | 660 (69.1) | 334 (67.2) | 326 (71.2) | 0.208 |
Treatment, n (%) | ||||
Defibrillation | 33 (3.5) | 18 (3.6) | 15 (3.3) | 0.908 |
ventilation | 624 (65.3) | 312 (62.8) | 312 (68.1) | 0.096 |
Laboratory indicators, median [IQR] | ||||
NMLR | 6.40 [3.34, 12.61] | 5.67 [3.08, 10.17] | 7.30 [3.64, 15.01] | < 0.001 |
WBC × 10^9/L | 9.40 [6.60, 14.60] | 8.90 [6.50, 13.80] | 10.25 [6.80, 15.57] | 0.013 |
Basophils, × 10^9/L | 0.03 [0.01, 0.05] | 0.03 [0.01, 0.05] | 0.02 [0.00, 0.04] | < 0.001 |
Eosinophils, × 10^9/L | 0.09 [0.02, 0.22] | 0.11 [0.03, 0.24] | 0.07 [0.01, 0.18] | < 0.001 |
Lymphocytes, × 10^9/L | 1.21 [0.77, 1.84] | 1.32 [0.88, 1.91] | 1.12 [0.70, 1.74] | 0.001 |
Monocytes, × 10^9/L | 0.51 [0.35, 0.78] | 0.53 [0.37, 0.78] | 0.48 [0.32, 0.77] | 0.056 |
Neutrophils, × 10^9/L | 7.12 [4.48, 11.91] | 6.53 [4.21, 10.95] | 7.83 [4.72, 12.88] | 0.004 |
pco2, mmHg | 43.00 [36.00, 52.00] | 44.00 [37.00, 53.00] | 42.00 [35.00, 52.00] | 0.171 |
aado2_calc, mmHg | 259.50 [171.95, 488.62] | 249.50 [167.25, 496.75] | 267.38 [174.51, 480.92] | 0.495 |
PaO2/FiO2 | 178.00 [88.79, 325.00] | 200.00 [97.50, 355.00] | 164.50 [82.00, 302.25] | 0.003 |
ph | 7.32 [7.21, 7.39] | 7.33 [7.25, 7.39] | 7.29 [7.18, 7.37] | < 0.001 |
Lactate, mmol/L | 2.80 [1.70, 5.10] | 2.40 [1.50, 4.30] | 3.50 [1.80, 6.50] | < 0.001 |
Hematocrit, % | 32.40 [27.50, 38.30] | 33.10 [28.00, 39.30] | 31.40 [26.92, 37.70] | 0.008 |
Hemoglobin, g/L | 10.50 [8.80, 12.40] | 10.80 [9.00, 12.80] | 10.00 [8.60, 12.07] | < 0.001 |
Platelet, × 10^9/L | 194.00 [142.00, 266.50] | 192.00 [147.00, 262.00] | 197.00 [130.00, 278.00] | 0.806 |