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Table 2 Univariate and multivariate Cox analysis of overall survival before PSM

From: Comparison of trimodality therapy and neoadjuvant chemotherapy combined with radical cystectomy for the survival of muscle-invasive bladder cancer: a population-based analysis

Characteristics

Univariable

Multivariable

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Age

      

 < 68 years

Reference

  

Reference

  

 ≥ 68 years

2.046

1.692–2.473

< 0.001

1.610

1.320–1.963

< 0.001

Sex

      

 Male

Reference

  

Reference

  

 Female

1.508

0.878–1.276

0.557

0.976

0.804–1.186

0.809

Race

      

 White

Reference

  

Reference

  

 Black

1.364

1.020–1.825

0.036

1.267

0.943–1.701

0.116

 Other/Unknown

1.002

0.697–1.441

0.991

0.986

0.686–1.419

0.941

Marital status

      

 Married

Reference

  

Reference

  

 Unmarried/unknown

1.384

1.175–1.631

< 0.001

1.326

1.118–1.572

< 0.001

Grade

      

 I/II

Reference

  

Reference

  

 III/IV

1.949

1.008–3.768

0.047

2.099

1.084–4.064

0.028

 Unknown

1.962

0.955–4.033

0.067

2.159

1.048–4.444

0.037

T stage

      

 T2

Reference

  

Reference

  

 T3–4a

1.044

0.846–1.288

0.043

1.488

1.194–1.854

< 0.001

Therapy

      

 TMT

Reference

  

Reference

  

 NAC + RC

0.334

0.267–0.418

< 0.001

0.358

0.281–0.457

< 0.001

  1. TMT: trimodality therapy; NAC: neoadjuvant chemotherapy; RC: radical cystectomy; CI: confidence interval; HR: hazard ratio
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European Journal of Medical Research

ISSN: 2047-783X

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