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Table 3 Univariate and multivariate Cox analysis of OS after PSM

From: Comparison of trimodality therapy and neoadjuvant chemotherapy combined with radical cystectomy for the survival of muscle-invasive bladder cancer: a population-based analysis

Characteristics

Univariable

Multivariable

Hazard ratio

95% CI

P

Hazard ratio

95% CI

P

Age

      

 < 68 years

Reference

  

Reference

  

 ≥ 68 years

1.974

1.538–2.535

 < 0.001

1.929

1.482–2.510

< 0.001

Sex

      

 Male

Reference

  

Reference

  

 Female

1.103

0.832–1.462

0.496

1.136

0.845–1.527

0.309

Race

      

 White

Reference

  

Reference

  

 Black

1.367

0.873–2.139

0.172

1.079

0.682–1.702

0.745

 Other/Unknown

0.981

0.572–1.685

0.946

0.978

0.567–1.685

0.935

Marital status

      

 Married

Reference

  

Reference

  

 Unmarried/unknown

1.529

1.196–1.956

 < 0.001

1.326

1.118–1.572

< 0.001

Grade

      

 I/II

Reference

  

Reference

  

 III/IV

7.054

0.989–50.307

0.047

6.444

0902–44.023

0.063

 Unknown

7.596

1.013–56.940

0.049

7.114

0.947–53.414

0.056

T stage

      

 T2

Reference

  

Reference

  

 T3–4a

1.286

0.944–1.751

0.003

1.068

0.775–14,731.854

< 0.001

Therapy

      

 TMT

Reference

  

Reference

  

 NAC + RC

0.311

0.237–0.408

 < 0.001

0.350

0.270–0.453

< 0.001

  1. TMT: trimodality therapy; NAC: neoadjuvant chemotherapy; RC: radical cystectomy; CI: confidence interval; HR: hazard ratio