Table 1 Baseline demographic and clinical data of the study patients according to tertiles of triglyceride–glucose index
Characteristic | Total N = 1061 | Tertile 1 N = 353 | Tertile 2 N = 354 | Tertile 3 N = 354 | P value |
|---|---|---|---|---|---|
Age, mean (SD), yrs | 61.8 (10.5) | 62.3 (11.1) | 60.8 (10.3) | 62.2 (10.1) | 0.096 |
Male, No. (%) | 789 (74.4) | 271 (76.8) | 258 (72.9) | 260 (73.4) | 0.441 |
SBP, mean (SD), mmHg | 141.7 (25.2) | 142.1 (24.5) | 143.0 (25.6) | 140.1 (25.5) | 0.284 |
DBP, mean (SD), mmHg | 78.9 (13.6) | 79.6 (13.5) | 79.6 (13.7) | 77.4 (13.4) | 0.048 |
Heart rate, mean (SD), beats/min | 80.7 (14.9) | 78.9 (14.0) | 81.5 (16.0) | 81.8 (14.4) | 0.020 |
Medical history and risk factors, No. (%) | |||||
Hypertension | 983 (92.6) | 316 (89.5) | 336 (94.9) | 331 (93.5) | 0.017 |
Diabetes mellitus | 559 (52.7) | 130 (36.8) | 178 (50.3) | 251 (70.9) | < 0.001 |
Current smoker | 193 (18.2) | 70 (19.8) | 60 (16.9) | 63 (17.8) | 0.594 |
Atrial fibrillation | 89 (8.4) | 31 (8.8) | 29 (8.2) | 29 (8.2) | 0.948 |
Cerebrovascular disease | 197 (18.6) | 63 (17.8) | 61 (17.2) | 73 (20.6) | 0.466 |
Valvular disease | 34 (3.2) | 14 (4.0) | 12 (3.4) | 8 (2.3) | 0.424 |
Peripheral arterial disease | 104 (9.8) | 30 (8.5) | 34 (9.6) | 40 (11.3) | 0.451 |
Dialysis modality, No. (%) | 0.048 | ||||
Hemodialysis | 975 (91.9) | 329 (93.2) | 331 (93.5) | 315 (89.0) | |
Peritoneal dialysis | 86 (8.1) | 24 (6.8) | 23 (6.5) | 39 (11.0) | |
Vintage, years | 0.308 | ||||
< 1 | 220 (20.7) | 73 (20.7) | 68 (19.2) | 79 (22.3) | |
1–5 | 490 (46.2) | 156 (44.2) | 163 (46.0) | 171 (48.3) | |
5–10 | 278 (26.2) | 94 (26.6) | 104 (29.4) | 80 (22.6) | |
≥ 10 | 73 (6.9) | 30 (8.5) | 19 (5.4) | 24 (6.8) | |
Cause of dialysis, No. (%) | < 0.001 | ||||
Diabetes mellitus | 326 (30.7) | 75 (21.2) | 105 (29.7) | 146 (41.2) | |
Hypertension | 129 (12.2) | 54 (15.3) | 44 (12.4) | 31 (8.8) | |
Glomerulonephritis | 259 (24.4) | 115 (32.6) | 74 (20.9) | 70 (19.8) | |
Other/unknown | 347 (32.7) | 109 (30.9) | 131 (37.0) | 107 (30.2) | |
Insulin therapy, No. (%) | 353 (33.3) | 76 (21.5) | 106 (29.9) | 171 (48.3) | < 0.001 |
Index presentation, No. (%) | 0.543 | ||||
AMI | 628 (59.2) | 202 (57.2) | 209 (59.0) | 217 (61.3) | |
Non-AMI | 433 (40.8) | 151 (42.8) | 145 (41.0) | 137 (38.7) | |
Hemoglobin, g/L | 105.2 (19.9) | 104.4 (19.3) | 105.5 (19.5) | 105.6 (21.0) | 0.651 |
Glucose, mmol/L | 6.3 [4.8, 9.1] | 4.7 [4.2, 5.7] | 6.2 [5.0, 8.0] | 9.9 [7.3, 13.4] | < 0.001 |
Serum creatinine, mg/dl | 8.6 [6.7, 11.0] | 8.4 [6.9, 10.5] | 9.1 [7.0, 11.6] | 8.1 [6.3, 10.8] | 0.004 |
TG, mmol/L | 1.6 [1.1, 2.3] | 1.0 [0.8, 1.3] | 1.7 [1.4, 2.1] | 2.5 [1.9, 3.4] | < 0.001 |
TC, mmol/L | 3.7 [3.1, 4.5] | 3.5 [2.9, 4.0] | 3.7 [3.2, 4.4] | 4.0 [3.2, 4.9] | < 0.001 |
HDL-C, mmol/L | 0.9 [0.7, 1.1] | 1.0 [0.8, 1.2] | 0.8 [0.7, 1.0] | 0.8 [0.7, 1.0] | < 0.001 |
LDL-C, mmol/L | 2.1 [1.6, 2.8] | 2.0 [1.6, 2.5] | 2.2 [1.7, 2.8] | 2.2 [1.7, 3.0] | < 0.001 |
TyG index | 9.1 [8.5, 9.5] | 8.3 [8.0, 8.5] | 9.1 [8.9, 9.2] | 9.8 [9.6, 10.1] | < 0.001 |
Procedure characteristic, No. (%) | |||||
Radial access | 823 (77.6) | 264 (74.8) | 281 (79.4) | 278 (78.5) | 0.298 |
Any left main disease | 118 (11.1) | 35 (9.9) | 45 (12.7) | 38 (10.7) | 0.477 |
Multivessel disease | 896 (84.4) | 285 (80.7) | 295 (83.3) | 316 (89.3) | 0.006 |
Moderate or severe calcification | 473 (44.6) | 156 (44.2) | 165 (46.6) | 152 (42.9) | 0.607 |
Gensini score | 52.0 [31.0, 82.0] | 48.0 [27.0, 76.0] | 54.0 [32.0, 84.0] | 54.0 [36.0, 84.0] | 0.016 |
PCI treatment | 746 (70.3) | 244 (69.1) | 247 (69.8) | 255 (72.0) | 0.673 |
Discharge medications, No. (%) | |||||
Dual antiplatelet therapy | 922 (86.9) | 308 (87.3) | 312 (88.1) | 302 (85.3) | 0.522 |
ACE inhibitor or ARB | 488 (46.0) | 174 (49.3) | 155 (43.8) | 159 (44.9) | 0.300 |
Beta-blocker | 857 (80.8) | 269 (76.2) | 293 (82.8) | 295 (83.3) | 0.028 |
Calcium-channel blocker | 684 (64.5) | 241 (68.3) | 225 (63.6) | 218 (61.6) | 0.162 |
Statin | 994 (93.7) | 328 (92.9) | 331 (93.5) | 335 (94.6) | 0.635 |