Skip to main content

Table 1 Comparison between MBE and non-MBE groups after MT in patients with ALVOS

From: The risk and outcome of malignant brain edema in post-mechanical thrombectomy: acute ischemic stroke by anterior circulation occlusion

 

All patients

(N = 155)

non-MBE group

(N = 125)

MBE group

(N = 30)

P

Age, median (IQR), years

64(54–72)

65(54–73)

61(56.25–69.5)

0.231

Male, n (%)

102(65.8)

83(66.4)

19(63.3)

0.750

Medical history, n (%)

    

 Hypertension

94(60.6)

74(59.2)

20(66.7)

0.452

 Diabetes mellitus

41(26.5)

36(28.8)

5(16.7)

0.176

 Coronary heart disease

29(18.7)

26(20.8)

3(10.0)

0.173

 Past history of stroke

36(23.2)

31(24.8)

5(16.7)

0.343

 Atrial fibrillation

53(34.2)

46(36.8)

7(23.3)

0.163

 Smoking

77(49.7)

62(49.6)

15(50.0)

0.969

 Alcohol use

71(45.8)

56(44.8)

15(50.0)

0.608

Clinical and imaging characteristics

    

 NIHSS score at admission, median (IQR), score

14(11–17)

14(11–17)

16(12–19)

0.074

 Baseline ASPECT score, median (IQR), score

8(8–10)

9(8–10)

8(6–9)

 < 0.001

 Present HMCAS, n (%)

79(51.0)

73(58.4)

6(20.0)

 < 0.001

 Signs of early infarction, n (%)

81(52.3)

57(45.6)

24(80.0)

0.001

TOAST classification, n (%)

   

0.572

 LAA

97(62.6)

77(61.6)

20(66.7)

 

 Cardioembolic

42(27.1)

36(28.8)

6(20.0)

 

 Undetermined or others

16(10.3)

12(9.6)

4(13.3)

 

Occluded vessel region, n (%)

   

0.193

 ICAT

29(18.7)

20(16.0)

9(30.0)

 

 MCA M1

85(54.8)

73(58.4)

12(40.0)

 

 MCA M2

13(8.4)

11(8.8)

2(6.7)

 

 ICA + MCA

28(18.1)

21(16.8)

7(23.3)

 

Time from onset to imaging,

median (IQR), min

187(105–336)

203(106.5–349.5)

159.5(87–292.75)

0.305

OTP, median (IQR), min

355(195–524)

375(206–545)

273(176.75–460.25)

0.162

Intravenous thrombolysis, n (%)

41(26.5)

33(26.4)

8(26.7)

0.976

Angiographic favorable collaterals, n (%)

54(34.8)

49(39.2)

5(16.7)

0.020

Number of retrieval attempts, median (IQR), count

1(1–2)

1(1–2)

2(1–4)

0.018

Balloon dilatation, n (%)

18(11.6)

16(12.8)

2(6.7)

0.532

Stent implantation, n (%)

7(4.5)

6(4.8)

1(3.3)

1.000

Revascularization (mTICI ≥ 2b), n (%)

130(83.9)

115(92.0)

15(50.0)

 < 0.001

Favorable clinical outcome (mRS ≤ 2), n (%)

68(43.9)

64(51.2)

4(13.3)

 < 0.001

  1. MBE, malignant brain edema; NIHSS, National Institutes of Health Stroke Scale; ASPECT, Alberta Stroke Program Early CT; HMCAS, hyperdense middle cerebral artery sign; TOAST, Trial of Org 10172 in Acute Stroke Treatment; LAA, large-artery atherosclerosis; ICAT, internal carotid artery terminal; MCA M1, middle cerebral artery M1 segment; MCA M2, middle cerebral artery M2 segment; ICA, internal carotid artery; MCA, middle cerebral artery; OTP, time from onset to puncture; mTICI, modified Thrombolysis in Cerebral Infarction; mRS, modified Rankin Scale
Back to article page

European Journal of Medical Research

ISSN: 2047-783X

Contact us