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Table 3 Univariable analysis of predictive factors for death in hospital

From: A dynamic online nomogram for predicting death in hospital after aneurysmal subarachnoid hemorrhage

Variable

Development cohort

Validation cohort

Odds ratio (95% CI)

p value

Odds ratio (95% CI)

p value

Sex

1.29 (0.77, 2.16)

0.335

0.76 (0.36, 1.60)

0.471

Age

0.99 (0.97, 1.01)

0.271

0.97 (0.96, 0.98)

 < 0.001

Level on GCS score

 Mild (13–15 points)

1 [Reference]

1 [Reference]

1 [Reference]

1 [Reference]

 Moderate (9–12 points)

0.48 (0.23, 1.00)

 < 0.001

0.11 (0.04, 0.30)

 < 0.001

 Severe (3–8 points)

0.19 (0.11, 0.33)

0.017

0.22 (0.08, 0.63)

0.005

 MAP, mmHg

0.99 (0.98, 1.00)

0.069

0.98 (0.98, 0.99)

 < 0.001

 Hypertension (Yes vs No)

0.65 (0.40, 1.07)

0.089

0.12 (0.07, 0.20)

 < 0.001

 Diabetes (Yes vs No)

0.57 (0.26, 1.27)

0.171

0.27 (0.09, 0.80)

0.019

Hunt–Hess grade

 I, II, III

1 [Reference]

1 [Reference]

1 [Reference]

1 [Reference]

 IV, V

1.25 (0.45, 3.45)

 < 0.001

1.05 (1.01, 1.09)

0.002

mFS grade

 0, I, II

1 [Reference]

1 [Reference]

1 [Reference]

1 [Reference]

 III, IV

1.42 (1.70, 2.87)

 < 0.001

1.25 (1.14, 1.43)

 < 0.001

NIHSS score

1.15 (1.04, 1.27)

 < 0.001

1.05 (1.02, 1.08)

 < 0.001

Smoking

5.47 (0.74, 40.32)

0.095

0.11 (0.01, 1.84)

0.126

Drink abuse

4.03 (0.54, 29.89)

0.173

0.11 (0.01, 1.84)

0.126

Blood glucose

0.82 (0.76, 0.87)

 < 0.001

1.11 (1.01, 1.22)

0.029

Serum calcium level

0.44 (0.08, 2.56)

0.361

1.60 (0.09, 30.07)

0.753

Inflammatory index

 Leukocyte count

0.88 (0.85, 0.92)

 < 0.001

1.20 (1.11, 1.30)

 < 0.001

 Neutrophil count

0.88 (0.84, 0.92)

 < 0.001

1.16 (1.07, 1.26)

 < 0.001

 Lymphocyte count

0.96 (0.79, 1.16)

0.653

1.28 (1.00, 1.64)

0.050

 Monocyte count

0.26 (0.15, 0.47)

 < 0.001

6.73 (3.16, 14.34)

 < 0.001

 Platelet count

1.00 (1.00, 1.00)

0.700

1.00 (1.00, 1.01)

0.583

 NLR

0.96 (0.93, 0.99)

 < 0.001

0.81 (0.77, 0.85)

 < 0.001

 MLR

0.31 (0.17, 0.57)

 < 0.001

0.05 (0.03, 0.11)

 < 0.001

 PLR

1.00 (1.00, 1.00)

0.992

1.00 (0.99, 1.00)

0.073

 NWR

0.05 (0.00, 0.78)

0.032

0.07 (0.04, 0.11)

 < 0.001

 MNM

1.03 (1.01, 1.06)

 < 0.001

1.13 (1.08, 1.18)

 < 0.001

  1. GCS Glasgow Coma Scale, MAP mean arterial pressure, mFS grade modified Fisher grade, NIHSS National Institutes of Health Stroke Scale, NLR neutrophil-to-lymphocyte ratio, MLR monocyte-to-lymphocyte ratio; PLR platelet-to-lymphocyte ratio, NWR neutrophil-to-leukocyte ratio, MNM multiplication to neutrophil and monocyte counts
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European Journal of Medical Research

ISSN: 2047-783X

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