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Table 2 Correlation between soluble immune checkpoint levels and immunoglobulin (Ig) and liver function

From: Soluble immune checkpoints are elevated in patients with primary biliary cholangitis

 

CD134

PD-1

PD-L1

LAG-3

TIM-3

r

P

r

P

r

P

r

P

r

P

ALP

− 0.13

0.34

0.38

0.01

0.38

0.01

− 0.24

0.08

0.19

0.18

IgA

0.34

0.03

0.15

0.40

0.16

0.31

0.31

0.06

− 0.03

0.85

IgG

0.34

0.04

0.48

0.00

0.48

0.00

0.52

0.00

− 0.07

0.68

IgM

− 0.097

0.56

0.14

0.42

− 0.027

0.87

0.27

0.12

0.18

0.29

AST

0.18

0.19

0.39

0.00

0.39

0.00

0.36

0.01

0.19

0.15

TB

0.33

0.01

0.26

0.06

0.23

0.08

0.24

0.08

0.56

 < 0.0001

TBA

0.23

0.09

0.45

0.00

0.45

0.00

0.41

0.00

0.01

0.96

CHE

− 0.5

 < 0.0001

− 0.31

0.02

− 0.31

0.02

− 0.37

0.01

− 0.37

0.00