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Table 2 Combined and dose reduction indexes of GLC-82 cells treated with CDDP and TA for 24 h

From: Synergistic anticancer activity of cisplatin combined with tannic acid enhances apoptosis in lung cancer through the PERK-ATF4 pathway

Growth inhibition ratio (%)

CI

CDDP

TA

C (μg/mL)

DRI

C (μg/mL)

DRI

Single

Combined

Single

Combined

20

0.64

2.4

1

2.40

481

106

4.53

28

0.71

3

1.25

2.40

513

148

3.45

50

0.76

5

2

2.50

595

212

2.80

56

0.94

5.5

2.5

2.20

612

298

2.06

70

1.15

7.7

4

1.93

673

425

1.58

77

1.38

9

5

1.80

717

595

1.21

  1. CDDP: cisplatin; TA: tannin; CI: combined index; DRI: dose reduction index