Table 1 The Frequencies and HSP70 expression considering the different clinicopathological parameters
Clinicopathological characteristics | Groups | HSP70 expression | Frequency | Sig./test | ||
|---|---|---|---|---|---|---|
Negative | low | High | ||||
Gender | Male | 0 | 9 (29%) | 22 (71%) | 31 (62%) | 0.041/X2 |
Female | 0 | 1 (5.3%) | 18 (94.7%) | 19 (38%) | ||
Age groups |  ≤ 55 years | 0 | 4 (25%) | 12 (75%) | 16 (32%) | 0.544/X2 |
 > 55 years | 0 | 6 (17.6%) | 28 (82.4%) | 34 (68%) | ||
Tumor site | Tongue | 0 | 2 (11.8%) | 15 (88.2%) | 17 (34%) | 0.280/ANOVA |
Lips and cheeks | 0 | 3 (30%) | 7 (70%) | 10 (20%) | ||
Floor of the mouth | 0 | 0 | 8 (100%) | 8 (16%) | ||
Palate | 0 | 2 (40%) | 3 (60%) | 5 (10%) | ||
Alveolar ridge | 0 | 3 (30%) | 7 (70%) | 10 (20%) | ||
TNM stage | Stage I and II | 0 | 10 (38.5%) | 16 (61.5%) | 26 (52%) | 0.001/X2 |
Stage III and IV | 0 | 0 | 24 (100%) | 24 (48%) | ||
Tumor size | T1 and T2 | 0 | 10 (35.7%) | 18 (64.3%) | 28 (56%) | 0.002/X2 |
T3 and T4 | 0 | 0 | 22 (100%) | 22 (44%) | ||
Nodal involvement | Negative | 0 | 10 (38.5%) | 16 (61.5%) | 26 (52%) | 0.001/X2 |
Positive | 0 | 0 | 24 (100%) | 24 (48%) | ||
Distant metastasis | Absent | 0 | 10 (25%) | 30 (75%) | 40 (80%) | 0.077/X2 |
Present | 0 | 0 | 10 (100%) | 10 (20%) | ||
Incidence of recurrence | Absent | 0 | 10 (31.3%) | 22 (68.8%) | 32 (64%) | 0.008/X2 |
Present | 0 | 0 | 18 (100%) | 18 (36%) | ||
The studied groups | Normal oral mucosa | 5 (100%) | 0 | 0 | 5 (6.7%) | 0.000/ANOVA |
Free surgical margin | 0 | 14 (70%) | 6 (30%) | 20 (26.7%) | ||
OSCC | 0 | 10 (20%) | 40 (80%) | 50 (66.7%) | ||
Free surgical margin grading | Mild dysplasia | 0 | 9 (100%) | 0 (0%) | 9 (45%) | 0.023/ANOVA |
Moderate dysplasia | 0 | 3 (50%) | 3 (50%) | 6 (30%) | ||
Sever dysplasia | 0 | 2 (40%) | 3 (60%) | 5 (25%) | ||
Carcinoma histologic grading | Well differentiated | 0 | 10 (62.5%) | 6 (37.5%) | 16 (32%) | 0.000/ANOVA |
Moderately diff | 0 | 0 | 20 (100%) | 20 (40%) | ||
Poorly diff | 0 | 0 | 14 (100%) | 14 (28%) | ||