Table 1 Baseline characteristics of the patients
Variables | Remimazolam (n = 60) | Propofol or midazolam (n = 46) | P-value |
|---|---|---|---|
Age, years | 61.0 ± 13.5 | 57.2 ± 16.1 | 0.182 |
Age group | 0.542 | ||
< 65 | 37 (61.7) | 31 (67.4) | |
≥ 65 | 23 (38.3) | 15 (32.6) | |
Male | 42 (70.0) | 28 (60.9) | 0.325 |
APACHE II score | 22.0 (19.3, 27.0) | 24.0 (22.0, 28.0) | 0.175 |
Glasgow coma scale | 5.0 (3.0, 9.8) | 4.0 (3.0, 9.0) | 0.083 |
Cerebral hemorrhage | 17 (28.3) | 14 (30.4) | 0.814 |
Shock | 15 (25.0) | 8 (17.4) | 0.346 |
Hepatic insufficiency | 14 (23.3) | 14 (30.4) | 0.411 |
Renal insufficiency | 14 (23.3) | 8 (17.4) | 0.455 |
Sepsis | 5 (8.3) | 2 (4.3) | 0.696 |
Type of ICU admission | 0.090 | ||
Other departments or medical institutions | 32 (53.3) | 32 (69.6) | |
Emergency | 28 (46.7) | 14 (30.4) | |
The time from admission to ICU to the use of the test drug, h | 3.0 (0.0, 26.5) | 6.0 (0.0, 22.0) | 0.770 |