Table 3 Outcomes
Variables | Remimazolam (n = 60) | Propofol or midazolam (n = 46) | P-value |
|---|---|---|---|
RASS score | − 4.0 (− 4.0, -3.0) | − 4.0 (− 4.0, − 3.0) | 0.317 |
Duration of mechanical ventilation, hours | 75.0 (46.3, 158.8) | 114.0 (70.0, 254.0) | 0.038 |
All-cause ICU mortality | 22 (36.7%) | 8 (17.4%) | 0.032 |
Length of ICU, days | 6.0 (4.0, 10.0) | 7.0 (4.0, 19.0) | 0.450 |
Length of stay in hospital, days | 10.0 (6.0, 24.8) | 21.0 (9.0, 33.0) | 0.061 |
Adverse events | |||
Tachycardia | 18 (30.0) | 16 (34.8) | 0.601 |
Hypotension | 11 (18.3) | 8 (17.4) | 1.000 |
Hypertension | 3 (5.0) | 4 (8.7) | 0.464 |
Cost of sedative per case, yuan | 907.3 (685.9, 1383.7) | 546.5 (308.2, 1250.4) | 0.001 |
Total Inpatient cost, yuan | 136,806.50 (86,932.05, 223,212.88) | 217,919.19 (91,237.08, 247,396.00) | 0.189 |
ICU Inpatient Costs, yuan | 101,399.74 (63,899.72, 191,501.65) | 104,766.62 (57,557.64, 231,638.21) | 0.684 |