Table 1 The baseline characteristics of included studies
Author | Year | Nation | Study design | Participants (n) | Male (%) | Age (y) | Type of stroke | Type of intervention | Cutoff (× 109/L) | Primary endpoints | Secondary endpoints | Follow-up | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fei et al. | 2020 | China | Retrospective cohort study | 146 | 63.01 | 60.21 ± 13.84 | ICH in basal ganglia | – | 5.4 | END (assessed by NIHSS and GCS) | Predictive value of SIRI | 3 | 5 |
Zhang et al. | 2020 | China | Retrospective cohort study | 178 | 34.83 | 57.64 ± 10.23 | aSAH | Coiling or Clipping | 4.105 | Functional outcome (assessed by GOS) | Predictive value of SIRI | 90 d | 7 |
Zhang et al. | 2020 | China | Retrospective cohort study | 125 | 36 | 56.00 ± 12.00 | aSAH | Coiling or Clipping | 3.63 | Vasospasm | Predictive value of SIRI | – | 5 |
Lattanzi et al. | 2021 | Italy | Retrospective cohort study | 184 | 47.28 | 75 (61–81) | AIS | EVT | 3.8 | Futile Recanalization (assessed by mRS) | Predictive value of SIRI | 90 d | 8 |
Li et al. | 2021 | China | Retrospective study based on a prospectively collected database | 403 in original cohort 262 in PSM cohort | 68.48 in original cohort 67.55 in PSM cohort | 58.56 ± 13.28 in original cohort 58.77 ± 13.56 in PSM cohort | ICH | Surgical intervention or conservative treatment | 2.76 | Functional outcomes (assessed by mRS) mortality | Predictive value of SIRI | 90 d for functional outcomes 30 d for mortality | 8 |
Shi et al. | 2021 | China | Retrospective cohort study | 135 | 40.74 | 57.03 ± 2.15 | aSAH | – | 5.91 | Poor outcome (assessed by GOS) | HHS, mFS, DCI, Pneumonia, AHC; Predictive value of SIRI | 90 d | 8 |
Yi et al. | 2021 | Korea | Retrospective study based on a prospectively collected database | 440 | 59.09 | 70.34 ± 12.87 | AIS | MT | 2.9 | Functional outcome (assessed by mRS) | Predictive value of SIRI | 90 d | 8 |
Yun et al. | 2021 | Korea | Retrospective multi-center | 680 | 68.24 | 56.43 ± 12.96 | aSAH | Surgery or Intervention | 3.2 | Functional outcome (assessed by mRS) | HHS, mFS, DCI, Vasospasm, AHC | 90 d | 8 |
Zhang et al. | 2021 | China | Retrospective cohort | 2450 (MIMIC-III database) | 52.29 | 68.17 ± 15.68 | Stroke | – | 3.8 | Mortality | Predictive value of SIRI | In-hospital, 30 d, 90 d, 1 year | 7 |
Li et al. | 2022 | China | Retrospective single-center | 303 | 58.75 | 69 (60–78) | AIS | IVT | – | Functional outcome (assessed by mRS) | Predictive value of SIRI | 90 d | 8 |
Ma et al. | 2022 | China | Prospective single-center | 63 | 68.84 | 65.35 ± 11.33 | AIS | IVT with alteplase | 1.01 | Functional outcome (assessed by mRS) | Severity of AIS (NIHSS) Predictive value of SIRI | 90 d | 9 |
Wang et al. | 2022 | China | Retrospective single-center cohort study | 375 | 65.87 | 61.9 ± 11.3 | AIS | – | 0.767 | END (assessed by NIHSS) | – | every day for 7 days after admission | 7 |
Yu et al. | 2022 | China | Retrospective single-center | 111 | 66.67 | 58.49 ± 15.01 | SAH | – | 6.478 | Functional outcome (assessed by mRS) | HHS, mFS, WFNS, DCI, Vasospasm, AHC, Rebleeding; Predictive value of SIRI | 90 d | 8 |
Zhou et al. | 2022 | China | Prospective single-center | 287 | 68.99 | 61.55 ± 13.08 | AIS | – | 1.349 | Functional outcome (assessed by mRS) | Predictive value of SIRI | 90 d | 9 |
Dang et al. | 2023 | China | Retrospective cohort | 2043 in original cohort 888 in PSM cohort (MIMIC-IV database) | 50.37 in original cohort 51.16 in PSM cohort | 70.4 (57.9–81.8) in original cohort 71.5 (58.6–82.8) in PSM cohort | AIS | Thrombolysis or thrombectomy | 4.57 | LOS ICU, LOS hospital, 90 d all-cause mortality | 30 d all-cause mortality 1-year all-cause mortality | In-hospital, 30 d, 90 d, 1-year | 7 |
Huang et al. | 2023 | China | Retrospective single-center cross-sectional study | 234 | 50.43 | 69 (57–78) | AIS | Thrombolysis or antiplatelet or anticoagulation | 1.79 | Functional outcome (assessed by mRS) | Severity of AIS (NIHSS) Predictive value of SIRI | – | 7 |
Wang JJ et al. | 2023 | China | Prospective single-center | 640 | 71.41 | 56.0 (48.0–64.0) | ICH | – | 5.03 | Functional outcome (assessed by mRS) | Complicated infections mortality | 30 d, 90 d, 1-year | 8 |
Yan et al. | 2023 | China | Retrospective single-center | 2802 | 61.67 | 68.02 ± 11.53 | AIS | – | 2.74 | SAP | Predictive value of SIRI | 7 days after admission | 6 |
Yu et al. | 2023 | China | Prospective single-center observational study | 378 | 66.93 | 63.54 ± 13.72 | ICH | – | – | SAP | Predictive value of SIRI | – | 7 |
Chu et al. | 2023 | China | Retrospective single-center | 240 | 33.75 | 66.00 (60.00–73.35) | AIS | IVT | 1.00 | Functional outcome (assessed by mRS) | Predictive value of SIRI | 90 d | 8 |
Hou et al. | 2023 | China | Retrospective cohort | 394 in original cohort 200 in PSM cohort | 44.87 | 55.6 ± 9.8 | aSAH | Coiling or Clipping | 5.36 | Functional outcome (assessed by mRS) | Predictive value of SIRI | 90 d | 9 |
Wang RH et al. | 2023 | China | Prospective multi-center observational | 320 | 66.56 | 62.5 (51.3–73) | ICH | Nasogastric tube surgery | 2.291 | SAP | Predictive value of SIRI | 7 days after admission | 9 |