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Table 2 Meta-analysis of different outcomes

From: Systemic inflammation response index as a clinical outcome evaluating tool and prognostic indicator for hospitalized stroke patients: a systematic review and meta-analysis

Items

Results

Studies, n

OR (95% CI)

P-value (Heterogeneity, I2 and P for Cochran Q)

Functional outcomes (assessed by GOS)

2

3.17 (1.51–6.65)

P = 0.002 (I2 = 0%, P = 0.36)

 Functional outcomes (assessed by mRS)

  Continuous variable

7

1.20 (1.07–1.34)

P = 0.001 (I2 = 66%, P = 0.008)

  Dichotomous variable

7

3.01 (2.00–4.54)

P < 0.0001 (I2 = 74%, P = 0.0007)

 Mortality

  In-hospital

3

1.68 (1.43–1.97)

P < 0.00001 (I2 = 0%, P = 0.37)

  1 month

4

1.50 (1.14–1.98)

P = 0.004 (I2 = 85%, P = 0.0002)

  3 months

3

1.77 (1.53–2.04)

P < 0.00001 (I2 = 0%, P = 0.77)

  1 year

2

1.65 (1.43–1.92)

P < 0.00001 (I2 = 1%, P = 0.31)

 SAP

  Continuous variable

3

1.11 (1.05–1.18)

P = 0.0006 (I2 = 66%, P = 0.05)

  Dichotomous variable

2

2.89 (2.23–3.75)

P < 0.00001 (I2 = 0%, P = 0.60)

END

2

1.78 (0.95–3.34)

P = 0.07 (I2 = 85%, P = 0.01)

 SAH-related clinical parameters

  HHS

4

2.70 (1.45–5.01)

P = 0.002 (I2 = 67%, P = 0.03)

  mFS

4

2.99 (1.57–5.70)

P = 0.0009 (I2 = 77%, P = 0.005)

  DCI

3

3.09 (2.16–4.43)

P < 0.00001 (I2 = 0%, P = 0.89)

  Vasospasm

3

1.67 (1.28–2.17)

P = 0.0001 (I2 = 79%, P = 0.008)

  AHC

4

1.90 (0.84–4.29)

P = 0.12 (I2 = 81%, P = 0.001)

 Predictive value of SIRI for poor outcome (assessed by GOS)

  SIRI

2

0.72 (0.63–0.82)

P < 0.00001 (I2 = 54%, P = 0.14)

  SIRI combining with clinical data

2

0.88 (0.83–0.94)

P < 0.0001 (I2 = 55%, P = 0.13)

Predictive value of SIRI for poor outcome (assessed by mRS)

12

0.72 (0.69–0.76)

P < 0.00001 (I2 = 78%, P < 0.00001)

Predictive value of SIRI for SAP

4

0.81 (0.74–0.89)

P < 0.00001 (I2 = 90%, P < 0.00001)

Items

Results

Studies, n

SMD or MD (95% CI)

P value heterogeneity (I2, P for Cochran Q)

SIRI values between different endpoints

Poor/good outcome (assessed by GOS)

2

0.72 (0.47–0.97)

P < 0.00001 (I2 = 42%, P = 0.19)

Poor/good outcome (assessed by mRS)

8

0.61 (0.52–0.69)

P < 0.00001 (I2 = 60%, P = 0.01)

SAP and Non-SAP

3

3.24 (1.56–4.91)

P = 0.0002 (I2 = 88%, P = 0.0002)

END and Non-END

2

0.37 (0.34–0.40)

P < 0.00001 (I2 = 0%, P = 0.79)