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Table 6 Association between HOMA-IR and Advanced Aging, Adjusted for Covariates

From: HOMA-IR is positively correlated with biological age and advanced aging in the US adult population

Variable

Model 1

Model 2

Model 3

Model 4

OR (95%)

P-value

OR (95%)

P-value

OR (95%)

P-value

OR (95%)

P-value

HOMA-IR

1.2 (1.1,1.2)

 < 0.001

1.1 (1.1,1.2)

 < 0.001

1.1 (1.1,1.2)

 < 0.001

1.0 (1.0,1.1)

 < 0.001

HOMA-IR group

 

 Q1

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 Q2

1.5 (1.3,1.7)

 < 0.001

1.4 (1.23,1.6)

 < 0.001

1.4 (1.2,1.7)

 < 0.001

1.2 (1.0,1.5)

 < 0.001

 Q3

2.0 (1.8,2.3)

 < 0.001

1.9 (1.6,2.1)

 < 0.001

1.9 (1.6,2.2)

 < 0.001

1.3 (1.1,1.5)

 < 0.001

 Q4

3.2 (2.8,3.7)

 < 0.001

3.0 (2.6,3.4)

 < 0.001

2.9 (2.5,3.4)

 < 0.001

1.6 (1.3,1.9)

 < 0.001

 p for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. Model 1: Non-adjusted
  2. Model 2: Adjusted for sex, ethnic
  3. Model 3: Adjusted for Model2 + Marital status, PIR, smoking, alcohol use
  4. Model 4: Adjusted for Model3 + BMI, ALT, AST, TG, HDL