Dengue virus serotype did not contribute to clinical severity or mortality in Taiwan’s largest dengue outbreak in 2015

Table 5 Subanalysis of mortality in DENV-2-infected patients

Demographic Characteristics^a	Survived	Death	P value	Logistic regression
Demographic Characteristics^a	n = 1460	n = 48	P value	P value	OR (95% CI)
Age (Years)	51 (0–91)	74 (48–88)	< 0.001	0.18	1.044 (0.980–1.113)
0–59	941 (64.5%)	6 (12.5%)	< 0.001	0.77	0.777 (0.144–4.202)
≥60	519 (35.5%)	42 (87.5%)	< 0.001	0.77	0.777 (0.144–4.202)
Sex
Male	752 (51.5%)	17 (35.4%)	0.028	0.027	3.294 (1.145–9.474)
Female	708 (48.5%)	31 (64.6%)	0.028	0.027	3.294 (1.145–9.474)
Severity
Dengue fever	1395 (95.5%)	10 (20.8%)	< 0.001	< 0.001	92.141 (30.775–275.874)
Severe dengue	65 (4.5%)	38 (79.2%)	< 0.001	< 0.001	92.141 (30.775–275.874)
Chronic disease^b
Diabetes mellitus	144 (10.3%)	14 (46.7%)	< 0.001	0.661	1.331 (0.370–4.782)
Hypertension	229 (16.3%)	15 (50.0%)	< 0.001	0.323	0.563 (0.181–1.757)
Congestive heart failure	25 (1.8%)	4 (13.3%)	< 0.001	0.111	4.048 (0.725–22.607)
COPD	58 (4.1%)	6 (20.0%)	< 0.001	0.461	1.705 (0.413–7.042)
Cerebrovascular disease	60 (4.3%)	3 (10.0%)	0.131
Moderate to severe CKD	18 (1.3%)	3 (10.0%)	< 0.001	0.796	0.789 (0.130–4.791)
Charlson comorbidity index score^b	1 (0–10)	5 (1–8)	< 0.001	0.293	1.276 (0.810–2010)

^aPresented as the numbers (%) except for average age and CCI score, which are shown as the median (range). The days PSO of these patients were ≤ 6 days. We excluded four patients from this analysis who did not die from severe dengue
^bN = 1,432, survival = 1,402, death = 30. COPD Chronic obstructive pulmonary disease, CKD Chronic kidney disease

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