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Table 3 Top 10 genes positive for mutation of risk groups

From: Correlation analysis of clinical, pathological, imaging and genetic features of ground-glass nodule featured lung adenocarcinomas between high-risk and non-high-risk individuals

Top 10 genes

High risk (N = 115, % among the total cases)

Non-high-risk (N = 358, % among the total cases)

P value

EGFR

72 (62.61)

220 (61.45)

0.824

TP53

29 (25.22)

37 (10.34)

 < 0.001*

ROS1

11 (9.57)

37 (10.34)

0.812

ERBB2

6 (5.22)

36 (10.06)

0.113

KRAS

15 (13.04)

17 (4.75)

0.002*

ALK

4 (3.48)

9 (2.51)

0.527

MET

4 (3.48)

8 (2.23)

0.497

RET

1 (0.87)

13 (3.63)

0.204

BRAF

8 (6.96)

17 (4.75)

0.357

MAP2K1

3 (2.61)

23 (6.42)

0.158

  1. *: P < 0.05 or P < 0.01 after Bonferroni correction is considered statistically different