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Table 3 Dosimetric and volumetric parameters between groups according to left lung volume

From: Cardiac protective techniques in left breast radiotherapy: rapid selection criteria for routine clinical decision making

 

BCS group (n = 56)

p*

Mastectomy group (n = 58)

 ≤ 1154 cc median (min–max)

 > 1154 cc median (min–max)

 ≤ 1208 cc median (min–max)

 > 1208 cc median (min–max)

p*

PTV volume (cc)

1178.2 (450.4–2273.0)

1162.9 (417.7–2060.0)

0.793

659.9 (188.4–1239.0)

474.6 (234.9–1040.8)

0.034

PTV min (Gy)

30.5 (9.5–40.1)

29.2 (10.6–49.7)

0.974

36.0 (13.6–50.4)

36.0 (20.1–50.4)

0.486

PTV max (Gy)

63.3 (53.8–69.0)

62.2 (51.6–66.6)

0.026

55.7 (51.5–64.9)

55.5 (53.2–65.3)

0.712

PTV mean (Gy)

52.3 (49.9–55.7)

51.7 (41.5–62.1)

0.206

51.1 (48.9–53.4)

51.4 (49.0–57.2)

0.100

Left lung volume (cc)

1056.5 (759.7–1164.0)

1244.4 (1171.5–1564.3)

0.000

1047.4 (740.7–1205.0)

1346.4 (1211.1–2241.0)

0.000

Lung min (Gy)

0.5 (0.1–1.0)

0.6 (0.1–2.7)

0.941

0.3 (0.1–3.4)

0.2 (0.0–0.9)

0.019

Lung max (Gy)

55.4 (48.7–66.4)

53.0 (47.3–61.4)

0.054

53.6 (50.1–66.6)

54.4 (49.8–58.1)

0.061

Lung mean (Gy)

13.2 (5.1–20.8)

11.7 (5.8–17.8)

0.511

15.6 (7.9–20.6)

15.3 (3.8–51.1)

0.911

Lung V5 (%)

40.2 (12.1–64.3)

36.3 (20.5–60.8)

0.651

44.0 (11.0–65.2)

41.1 (12.7–53.6)

0.100

Lung V10 (%)

30.5 (11.3–57.6)

29.7 (12.8–49.9)

0.628

37.0 (9.0–50.2)

34.5 (8.5–42.9)

0.335

Lung V20 (%)

25.8 (7.9–49.1)

22.5 (8.78–37.1)

0.501

30.0 (7.0–42.8)

29.0 (5.7–37.0)

0.381

Heart volume (cc)

674.1 (516.4–1064.1)

675.5 (466.3–996.4)

0.588

620.6 (441.1–848.1)

599.3(499.7–821.8)

0.898

Heart min (Gy)

0.8 (0.3–16.9)

0.8 (0.3–45.0)

0.571

0.4 (0.2–40.0)

0.3 (0.1–1.0)

0.009

Heart max (Gy)

52.0 (12.5–58.5)

50.0 (42.1–58.0)

0.015

51.0 (5.55–54.6)

51.8 (48.3–53.9)

0.214

Heart mean (Gy)

6.2 (2.6–10.2)

4.5 (2.1–9.1)

0.001

7.1 (4.2–916.2)

4.5 (2.5–8.0)

0.000

Heart V10 (%)

12.3 (2.2–37.0)

8.8 (4.0–20.0)

0.007

16.0 (9.5–38.0)

11.7 (6.0–20.0)

0.006

Heart V25 (%)

8.2 (0.1–50.0)

5.6 (2.4–18.0)

0.020

11.0 (5.2–32.0)

8.0 (3.5–17.0)

0.002

Heart V35 (%)

5.6 (0.5–30.0)

4.0 (1.7–16.0)

0.036

8.1 (1.9–28.0)

7.0 (2.4–15.0)

0.017

  1. BCS: Breast-conserving surgery, PTV: Planning target volume, n: number of patients, Gy: Gray, cc: cubic centimeter, max: maximum, min: minimum
  2. *Kruskal–Wallis test
  3. Bold values indicate the significant p values (p<0.05)