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Table 4 Dosimetric and volumetric parameters between groups according to left lung/heart volume ratio only in the mastectomy group (n = 58)

From: Cardiac protective techniques in left breast radiotherapy: rapid selection criteria for routine clinical decision making

 

Left lung/heart volume ratio

p*

 ≤ 1.92 median (min–max)

 > 1,92 median (min–max)

PTV volume (cc)

661.3 (188.4–1239.0)

454.0 (234.9–884.6)

0.016

PTV min (Gy)

36.0 (13.6–50.4)

36.0 (23.1–50.4)

0.625

PTV max (Gy)

55.5 (51.5–63.7)

56.2 (54.0–65.3)

0.102

PTV mean (Gy)

51.1 (48.9–53.4)

51.4 (50.0–57.2)

0.045

Left lung volume (cc)

1055.3 (740.7–1365.2)

1318.0 (1021.8–2241.0)

0.000

Lung min (Gy)

0.3 (0.1–3.4)

0.2 (0.1–2.4)

0.024

Lung max (Gy)

53.2 (49.8–66.6)

54.5 (5.6–58.1)

0.001

Lung mean (Gy)

15.8 (8.5–51.1)

14.8 (3.8–19.1)

0.229

Lung V5 (%)

44.0 (22.0–65.2)

40.0 (11.0–62.0)

0.029

Lung V10 (%)

37.0 (9.0–50.2)

33.0 (8.5–50.0)

0.095

Lung V20 (%)

30.0 (7.0–42.8)

28.0 (5.7–37.0)

0.117

Heart volume (cc)

667.8 (499.6–848.1)

576.0 (441.1–821.8)

0.004

Heart min (Gy)

0.5 (0.2–40.0)

0.3 (0.1–4.4)

0.002

Heart max (Gy)

51.0 (5.5–54.6)

52.1 (49.0–53.9)

0.027

Heart mean (Gy)

7.1 (4.5–16.2)

5.6 (2.5–8.3)

0.002

Heart V10 (%)

16.5 (8.1–39.0)

12.0 (6.0–20.0)

0.012

Heart V25 (%)

10.5 (5.2–32.0)

8.5 (3.5–17.0)

0.020

Heart V35 (%)

8.05 (1.9–28.0)

7.5 (2.4–15.0)

0.118

  1. PTV: Planning target volume, n: number of patient, Gy:Gray, cc:cubic cantimeter, max: maximum, min:minimum
  2. * Kruskal–Wallis test
  3. Bold values indicate the significant p values (p<0.05)