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Table 3 Risk factors of RA patients in active phase by logistic regression analysis

From: Effects of metformin therapy on HMGB1 levels in rheumatoid arthritis patients

Variables

Univariate

Multivariate

OR

95% CI

P

OR

95% CI

P

    

Model 1

Age

1.018

0.986–1.052

0.274

0.979

0.902–1.063

0.611

BMI

1.051

0.931–1.185

0.421

0.970

0.702–1.341

0.855

Course of disease

1.020

0.912–1.141

0.727

1.136

0.862–1.496

0.365

ESR

1.145

1.103–1.188

 < 0.001

1.184

1.095–1.281

 < 0.001

RF

1.051

1.034–1.069

 < 0.001

1.066

1.033–1.099

 < 0.001

    

Model 2

CRP

1.258

1.161–1.363

 < 0.001

1.551

1.110–2.169

0.100

IL-6

1.599

1.382–1.851

 < 0.001

1.985

1.244–3.169

0.040

TNF-α

0.981

0.931–1.032

0.455

0.892

0.688–1.156

0.388

CD4+

2.061

1.674–2.537

 < 0.001

1.865

1.447–2.380

 < 0.001

CD8+

1.082

0.956–1.224

0.214

1.053

0.760–1.460

0.755

CD4+/CD8+

1123.75

288.356–8775.293

 < 0.001

1793.381

252.208–12,780.682

 < 0.001

HMGB1

1.236

1.167–1.309

 < 0.001

1.258

1.133–1.397

 < 0.001

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European Journal of Medical Research

ISSN: 2047-783X

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