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Table 2 The roles and mechanisms of MAFG-AS1 in cancers

From: LncRNA MAFG-AS1 is involved in human cancer progression

Disease type

Cell lines

Functions

Related mechanisms

Refs.

Breast cancer

MCF7, MCF10, SUM149, HCC1937, BT474, Hs578T, SK-BR-3, MDA-MB-468, MDA-MB-231, and T47D

Cell proliferation, invasion, metastasis, apoptosis, and autophagy

miR-3612, FKBP4, miR-574-5p, SOD2, miR-150-5p, MYB, miR-339-5p, CDK2, miR-339-5p, MMP15, miR-3196, TFAP2A, JAK2, STAT3, and STC2

[43,44,45,46,47,48,49]

Lung cancer

H1373, H1975, H1650, HCC827, A549, PC-9, and Calu-3

Cell proliferation, migration, and invasion

miR-339-5p, MMP15, miR-744-5p, MAFG, miR-3196, and SOX12

[50,51,52]

Liver cancer

Huh7, HepG2, LM3, HCCLM3, Hep3B, and MHCC97-H

Cell proliferation, migration, invasion, and drug resistance

miR-3196, STRN4, E2F1, MAFG, miR-3196, OTX1, and miR-6852

[53,54,55,56,57,58]

Bladder cancer

HT01197, 5637, BIU87, EJ, RT4, J82, T24, HT-1376, UMUC3, and SVHUC1

Cell proliferation, migration, and invasion

miR-125b-5p, SphK1, HuR, PTBP1, miR-143-3p, COX-2, miR-143-3p, and SERPINE1

[59,60,61,62,63]

Colorectal cancer

HCT116, HT29, SW1116, SW480, and LoVo

Cell migration, proliferation, invasion, and glycolysis

miR-147b, NDUFA4, miRNA-149-3p, and HOXB8

[64,65,66]

Gastric cancer

MKN-45, AGS, and SGC7901

Cell proliferation, migration, and invasion

miR-505, and PLK1

[67, 68]

Esophageal cancer

EC9706, EC109, KYSE30, and KYSE150

Cell proliferation, migration, invasion, and aerobic glycolysis

miR-765, and PDX1

[69]

Prostate cancer

DU145, and PC-3

Cell proliferation and invasion

miR-3196, and NFIX

[70]

Pancreatic cancer

Capan 1, CFPAC-1, SW1990, and PANC-1

Cell proliferation and migration

NFKB1, and IGF1

[71]

Ovarian cancer

A2780, Caov-3, RMG-I, Caov-4, and CoC1

Cell invasion and migration

–

[72]

Glioma

U87, and U-118

Cell proliferation

miR-34a

[73]