Fig. 2
The performance of 6-GPS. A Kaplan–Meier curves depicting the survival difference between high-risk and low-risk EOCRCs classified by 6-GPS in TCGA. High, high-risk samples with surgery-only; Low, low-risk samples with surgery-only. B Multivariate Cox regression analysis in TCGA. C, D Circos plots showing the proportion of molecular subtypes in high-risk and low-risk EOCRCs. Kaplan–Meier curves depicting the survival difference between high-risk and low-risk EOCRCs in GSE39582 (E), GSE14333 (F), and combined dataset (G). HighACT, high-risk samples receiving ACT; LowACT, low-risk samples receiving ACT. H Histograms showing the difference in response to ACT between high-risk and low-risk samples in GSE72970 and GSE104645. SD/PD: stable/progressive disease; CR/PR: complete/partial response