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Table 1 Characteristics of the patients at baseline

From: Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure

Characteristics

NonH (N = 349)

SHC (N = 55)

Pa

SHT (N = 52)

Pb

MixH (N = 18)

Pc

Age

  < 38

258/349(73.9%)

37/55(67.3%)

0.302

35/52(67.3%)

0.316

13/18(72.2%)

1.000

  ≥ 38

91/349(26.1%)

18/55(32.7%)

0.302

17/52(32.7%)

0.316

5/18(27.8%)

1.000

BMI1

(23.10 ± 3.03)

(23.91 ± 2.90)

0.067

(25.37 ± 3.87)

0.000

(24.59 ± 2.45)

0.042

Fertility history

 Duration of attempt to conceive—yr

(4.80 ± 3.30)

(4.92 ± 3.56)

0.814

(4.89 ± 3.12)

0.853

(5.00 ± 3.25)

0.806

 Previous conception—no./total no. (%)

223/349(63.9%)

34/55(61.8%)

0.766

35/52(67.3%)

0.632

11/18(61.1%)

0.811

 Previous miscarriage—no./total no. (%)

195/349(55.9%)

31/55(56.4%)

0.946

31/52(59.6%)

0.612

10/18(55.6%)

0.979

 Previous live birth—no./total no. (%)

77/349(22.1%)

12/55(21.8%)

0.968

13/52(25.0%)

0.636

4/18(22.2%)

1.000

Ultrasonographic findings

 Antral follicle count in both ovaries

(14.01 ± 6.93)

(13.38 ± 7.74)

0.542

(17.35 ± 8.84)

0.002

(15.44 ± 12.35)

0.413

 Endometrial thickness—mm

(0.78 ± 0.24)

(0.75 ± 0.21)

0.355

(0.79 ± 0.26)

0.749

(0.79 ± 0.22)

0.846

Laboratory testing2

 Follicle-stimulating hormone—IU/liter

(7.34 ± 2.67)

(7.49 ± 2.67)

0.687

(6.40 ± 2.04)

0.016

(6.85 ± 2.46)

0.447

 Luteinizing hormone—IU/liter

(5.65 ± 4.94)

(4.77 ± 2.27)

0.198

(5.65 ± 4.94)

0.897

(4.61 ± 3.07)

0.380

 Estradiol—pg/ml

(82.42 ± 188.95)

(93.18 ± 202.75)

0.698

(103.03 ± 275.14)

0.493

(111.87 ± 261.15)

0.528

 Total testosterone—ng/dl

(22.69 ± 14.26)

(25.42 ± 23.09)

0.232

(25.14 ± 18.93)

0.374

(17.11 ± 10.26)

0.102

 Prolactin—ng/ml

(18.60 ± 16.51)

(17.71 ± 8.35)

0.694

(16.25 ± 8.52)

0.314

(15.40 ± 9.59)

0.415

 TSH—uIU/ml

(2.27 ± 1.12)

(2.27 ± 2.11)

0.999

(2.19 ± 0.83)

0.636

(2.43 ± 0.89)

0.532

  1. NonH, nonhyperlipidemia; SHC, simple hypercholesterolemia; SHT, simple hypertriglyceridemia; MixH, mixed hyperlipidemia
  2. Pa: NonH group VS SHC group; Pb: NonH group VS SHT group; Pc: NonH group VS MixH group
  3. 1 The body mass index is the weight in kilograms divided by the square of the height in meters
  4. 2 The baseline steroid hormones were measured at the early follicular phase, mostly on day 1 to 3 of the menstrual cycle
  5. Data were missing regarding TSH in 6 women, PRL in 3 women, TO in 2 women and endometrial thickness in 1 woman
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European Journal of Medical Research

ISSN: 2047-783X

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