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Table 2 Outcomes of controlled ovarian hyperstimulation and embryos

From: Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure

Characteristics1

NonH (N = 349)

SHC (N = 55)

Pa

SHT (N = 52)

Pb

MixH (N = 18)

Pc

No. of days of ovarian stimulation

(9.68 ± 2.15)

(9.67 ± 1.79)

0.991

(9.79 ± 1.68)

0.718

(9.78 ± 2.18)

0.845

Gonadotropin dosage—IU

(2060.19 ± 879.60)

(2132.27 ± 849.80)

0.571

(2107.21 ± 775.92)

0.715

(2080.56 ± 754.13)

0.923

Estradiol level on hCG trigger day—pg/ml

(3250.41 ± 1920.45)

(3033.78 ± 2101.70)

0.443

(3114.60 ± 2572.00)

0.651

(3277.39 ± 2267.59)

0.954

Endometrial thickness on hCG trigger day—mm

(1.00 ± 0.19)

(0.99 ± 0.18)

0.776

(1.06 ± 0.18)

0.026

(0.98 ± 0.19)

0.735

No. of oocytes retrieved

(10.53 ± 5.94)

(9.80 ± 5.33)

0.389

(10.92 ± 5.25)

0.654

(12.00 ± 10.61)

0.568

No. of good-quality embryos on day 5 or 6

(3.74 ± 2.77)

(3.00 ± 2.29)

0.033

(3.62 ± 2.83)

0.754

(4.11 ± 3.07)

0.587

Result on preimplantation genetic testing—no./total no. (%)

 Balanced euploid

517/1142(45.3%)

57/149(38.3%)

0.105

72/163(44.2%)

0.792

27/64(42.2%)

0.629

 Aneuploid

419/1142(36.7%)

72/149(48.3%)

0.006

54/163(33.1%)

0.376

26/64(40.6%)

0.526

 Chromosomal mosaic

201/1142(17.6%)

19/149(12.8%)

0.139

37/163(22.7%)

0.115

11/64(17.2%)

0.933

 Questionable

5/1142(0.4%)

1/149(0.7%)

0.522

0

1.000

0

1.000

Number of couples having no euploid embryos-no./total no. (%)

107/349(30.7%)

21/55(38.2%)

0.265

15/52(28.8%)

0.791

5/18(27.8%)

0.796

  1. NonH, nonhyperlipidemia; SHC, simple hypercholesterolemia; SHT, simple hypertriglyceridemia; MixH, mixed hyperlipidemia
  2. Pa: NonH group VS SHC group; Pb: NonH group VS SHT group; Pc: NonH group VS MixH group
  3. 1 The term hCG denotes human chorionic gonadotropin
  4. Data were missing regarding estradiol level on hCG trigger day in 1 woman