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Table 3 Cumulative pregnancy outcomes among different groups

From: Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure

Characteristics

NonH (N = 349)

SHC (N = 55)

Pa

SHT (N = 52)

Pb

MixH (N = 18)

Pc

Cumulative biochemical pregnancy—no. (%)

199/349(57.0%)

28/55(50.9%)

0.396

28/52(53.8%)

0.667

12/18(66.7%)

0.419

Cumulative clinical pregnancy—no. (%)

183/349(52.4%)

25/55(45.5%)

0.336

28/52(53.8%)

0.849

11/18(61.1%)

0.472

Cumulative ongoing pregnancy—no. (%)

167/349(47.9%)

22/55(40.0%)

0.278

24/52(46.2%)

0.819

10/18(55.6%)

0.524

Cumulative live-birth rate—no. (%)

164/349(47.0%)

22/55(40.0%)

0.334

23/52(44.2%)

0.710

10/18(55.6%)

0.478

Birth weight1

 Singleton

  No. of observations

162

22

 

22

 

10

 

  Mean weight—g

(3265.46 ± 568.98)

(3096.82 ± 588.63)

0.196

(3352.86 ± 612.76)

0.512

(3135.00 ± 496.12)

0.480

 Twin

  No. of observations

4

0

 

2

 

0

 

  Mean weight—g

2950.00 ± 353.55

0

–

2795.00 ± 1162.63

0.630

0

–

Cumulative pregnancy loss—no./total no. (%)

 Biochemical

21/199(10.6%)

4/28(14.3%)

0.788

2/28(7.1%)

0.822

1/12(8.3%)

1.000

 Clinical

22/199(11.1%)

5/28(17.9%)

0.466

5/28(17.9%)

0.466

1/12(8.3%)

1.000

  First trimester

17/199(8.5%)

4/28(14.3%)

0.526

3/28(10.7%)

0.981

1/12(8.3%)

1.000

  Second trimester

5/199(2.5%)

1/28(3.6%)

0.550

2/28(7.1%)

0.209

0

1.000

Good birth outcome2—no. (%)

130/349(37.2%)

19/55(34.5%)

0.699

19/52(36.5%)

0.921

8/18(44.4%)

0.539

Features of live births

 Duration of pregnancy—day

(270.49 ± 14.86)

(267.73 ± 19.29)

0.431

(268.70 ± 12.29)

0.580

(268.10 ± 13.07)

0.619

 No. of embryos transferred

(1.27 ± 0.59)

(1.09 ± 0.29)

0.023

(1.13 ± 0.46)

0.183

(1.40 ± 0.52)

0.511

 No. of embryo-transfer procedures

(1.27 ± 0.58)

(1.09 ± 0.29)

0.026

(1.13 ± 0.46)

0.201

(1.40 ± 0.52)

0.482

  1. NonH, nonhyperlipidemia; SHC, simple hypercholesterolemia; SHT, simple hypertriglyceridemia; MixH, mixed hyperlipidemia
  2. Pa: NonH group VS SHC group; Pb: NonH group VS SHT group; Pc: NonH group VS MixH group
  3. 1 Data were missing regarding singleton birth weight in 1 woman and twin birth weight in 1 woman
  4. 2 A good birth outcome was defined as a live birth at 37 weeks or more of gestation, with a birth weight between 2500 and 4000 g and without a major congenital anomaly