Maternal hypercholesterolemia would increase the incidence of embryo aneuploidy in couples with recurrent implantation failure

Table 4 The incidence of pregnancy and neonatal complications

Characteristics	NonH (N = 349)	SHC (N = 55)	P_a	SHT (N = 52)	P_b	MixH (N = 18)	P_c
Maternal
Gestational diabetes mellitus*	31/183(16.9%)	5/25(20.0%)	0.922	5/28(17.9%)	1.000	1/11(9.1%)	0.793
Preeclampsia or eclampsia*	5/183(2.7%)	1/25(4.0%)	0.541	0	1.000	0	1.000
Gestational hypertension*	11/183(6.0%)	3/25(12.0%)	0.487	4/28(14.3%)	0.233	0	1.000
Preterm delivery*	22/183(12.0%)	2/25(8.0%)	0.797	2/28(7.1%)	0.662	2/11(18.2%)	0.896
Placenta previa*	3/183(%)	0	1.000	0	1.000	0	1.000
Postpartum hemorrhage†	1/164(%)	0	1.000	0	1.000	0	1.000
Fetal, after 12 wk through neonatal period
Congenital anomaly‡	3/166(1.8%)	0	1.000	2/24(8.3%)	0.121	1/10(10.0%)	0.210
Low birth weight‡¹	12/166(7.2%)	1/22(4.5%)	0.985	3/24(12.5%)	0.624	1/10(10.0%)	0.545
Macrosomia‡²	11/166(6.6%)	0	1.000	1/24(4.2%)	0.989	0	1.000

NonH, nonhyperlipidemia; SHC, simple hypercholesterolemia; SHT, simple hypertriglyceridemia; MixH, mixed hyperlipidemia
P_a: NonH group VS SHC group; P_b: NonH group VS SHT group; P_c: NonH group VS MixH group
^* Evaluation was performed in all clinical pregnancies
^† Evaluation was performed during or after all deliveries
^‡ Evaluation was performed in all live newborns
¹ Low birth weight was defined as a value of less than 2500 g
² Macrosomia was defined as a birth weight of more than 4000 g

ISSN: 2047-783X