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Fig. 1 | European Journal of Medical Research

Fig. 1

From: Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Fig. 1

Differentially expressed piRNAs and the correlation between piRNA-MW557525 and clinical features. A Volcano map of the differential piRNAs in PIWIL2-iCSC compared with GFP-FB by high-throughput sequencing. B Heat map of the 50 most differentially expressed piRNAs. C piRNA-MW557525 expression level in NB cell lines (SK-N-SH, SH-SY5Y, SK-N-BE2, IMR32) compared with HEK293 according to RT-qPCR. D Relative piRNA-MW557525 expression was determined in 41 NB tissues and 33 adjacent nontumor tissues by RT-qPCR. E Expression of piRNA-MW557525 in different stages of neuroblastoma according to RT-qPCR. F The relationship between piRNA-MW557525 and patient survival. ns P > 005; *P < 0.05; ***P < 0.001

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