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Fig. 5 | European Journal of Medical Research

Fig. 5

From: Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Fig. 5

piRNA-MW557525 reduced the proliferation-, apoptosis- and invasion-related indicators in NB xenografts. A The protein levels of PCNA, MMP2, MMP9, Bcl-2, Bax, cleaved caspase-3 in tumors of nude mice were detected by WB, piRNA-MW557525 mimics and NC cells. B Immunofluorescence staining of the proliferation-, apoptosis- and invasion-related indicators. ns P > 0.05; *P < 0.05; ***P < 0.001. vs. piRNA-NC

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