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Fig. 7 | European Journal of Medical Research

Fig. 7

From: Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Fig. 7

Effect of piRNA-MW557525 on the cell cycle of NB cells and the expression of cycle-related proteins. A The cell phases of SK-N-SH and SH-SY5Y cells were analyzed by flow cytometry after transfection with piRNA-MW557525 mimics, inhibitor and corresponding NC. B The protein levels of p53, p21, cyclin E and CDK2 were detected using western blotting after piRNA-MW557525 transfection in vitro. C Cell cycle-related protein in tumors of nude mice were detected by WB. ns P > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001. vs. piRNA-NC

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European Journal of Medical Research

ISSN: 2047-783X

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