Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Table 3 The relationship between piRNA-MW557525 and the clinicopathological characteristics of NB patients

Characteristics	n	Percentage (%)	piRNA-MW557525 relative expression P
Clinicopathological features			0.0***
Adjacent noncancerous tissues	33	80.5
NB	41	100
Age			0.524
≥ 1.5	13	31.7
< 1.5	28	68.3
Sex			0.912
Male	18	43.9
Female	23	56.1
Location			0.692
Left retroperitoneal	22	53.7
Right retroperitoneal	18	43.9
Others	1	2.4
INSS			< 0.001
I + II	16	39.0
III + IV	25	61.0
Prognostic type			< 0.01
FH	13	31.7
UFH	28	68.3
Lymphatic metastasis			0.653
Yes	27	65.9
No	14	34.1
Bone marrow metastasis			0.725
Yes	31	75.6
No	10	24.4

NB, neuroblastoma; INSS, International Neuroblastoma Staging System; FH, favorable histology; UFH, unfavorable histology

ISSN: 2047-783X