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Table 2 Comparison of 18F-FAPI and 18F-FDG PET/CT in the evaluation of all the mediastinal and hilar lymph nodes

From: 18F-FAPI PET/CT performs better in evaluating mediastinal and hilar lymph nodes in patients with lung cancer: comparison with 18F-FDG PET/CT

 

18F-FAPI

18F-FDG

P value

True positive (No. of lymph nodes)

38

32

/

False positive (No. of lymph nodes)

7

30

/

False negative (No. of lymph nodes)

7

13

/

True negative (No. of lymph nodes)

85

62

/

Sensitivity (%)

84 [71, 93]

71 [57, 82]

0.031*

Specificity (%)

92 [85, 97]

67 [57, 76]

 <0 .001*

Accuracy (%)

90 [83, 94]

69 [60, 76]

 <0 .001*

PPV (%)

84 [71, 93]

52 [39, 64]

/

NPV (%)

92 [85, 97]

83 [72, 90]

/

  1. Data in brackets are 95% CIs. FAPI = fibroblast activation protein inhibitor, FDG fluorodeoxyglucose, 18F = fluorine 18, PPV positive predictive value, NPV negative predictive value
  2. *Indicates statistical significance