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Table 1 Baseline characteristics of the NHANES (2007–2012) study population in TyG tertiles

From: Exploring the association between triglyceride-glucose index and thyroid function

Characteristics

Overall

Reference range

Male

Female

TyG

8.43 ± 0.55

  

Demographics

 Age, years

41.44 ± 16.81

  

 Gender (%)

   

  Male

966 (52.57%)a

  

  Female

882 (47.73%)

  

 Race (%)

   

  Mexican American

292 (15.80%)

  

  Non-Hispanic Black

354 (19.16%)

  

  Non-Hispanic White

870 (47.08%)

  

  Other Hispanic

191 (10.34%)

  

  Other Race

141 (7.63%)

  

 Marital status (%)

   

  Married

891 (48.21%)

  

  Unmarried

813 (43.99%)

  

  Unknown

144 (7.79%)

  

 PIR (%)

   

  0–1

351 (18.99%)

  

  > 1

1360 (73.59%)

  

  Unknown

137 (7.41%)

  

 Education (%)

   

  < High school diploma

416 (22.51%)

  

  High school diploma

410 (22.19%)

  

  > High school diploma

1022 (55.30%)

  

 Alcohol use (%)

   

  Never

162 (8.77%)

  

  Former

218 (11.80%)

  

  Mild

548 (29.65%)

  

  Moderate

277 (14.99%)

  

  Heavy

416 (22.51%)

  

  Unknown

227 (12.28%)

  

 Smoke (%)

   

  Never

965 (52.22%)

  

  Former

347 (18.78%)

  

  Current

391 (21.16%)

  

  Unknown

145 (7.85%)

  

 BMI, kg/m2

27.07 ± 5.62

  

 WC, cm

93.38 ± 14.12

  

 SBP, mmHg

117.14 ± 15.49

  

 DBP, mmHg

68.44 ± 11.41

  

 MetS (%)

   

  No

1157 (84.5%)

  

  Yes

291 (15.75%)

  

 PA level (%)

   

  Low

614 (33.23%)

  

  Intermediate

618 (33.44%)

  

  High

616 (33.33%)

  

 Hypertension (%)

   

  No

1396 (75.54%)

  

  Yes

452 (24.46%)

  

 CVD (%)

   

  No

1620 (87.66%)

  

  Yes

84 (4.55%)

  

  Unknown

144 (7.79%)

  

Laboratory indices

 FPG, mmol/L

5.30 ± 0.43

3.33–5.56

3.33–5.56

 FBI, pmol/L

64.10 ± 46.98

12–150

12–150

 HbA1c, %

5.34 ± 0.36

4.3–6.0

4.3–6.0

 ALT, u/L

25.53 ± 27.39

11–47

7–30

 AST, u/L

26.03 ± 27.27

13–33

13–33

 Creatinine, umol/L

75.01 ± 18.06

61.88–114.92

53.04–97.24

 Uric acid, umol/L

318.17 ± 78.32

214.13–499.63

172.49–446.10

 BUN, mmol/L

4.28 ± 1.53

2.14–8.22

2.14–8.22

 TC, mg/dL

192.95 ± 40.06

 < 200

 < 200

 HDL, mg/dL

55.25 ± 15.16

 > 40

 > 50

 LDL, mg/dL

114.66 ± 34.55

 < 135

 < 135

 Hemoglobin, g/dL

14.37 ± 1.51

19–65 years: 13.1–17.5

 > 65 years: 11.4–17.1

19–65 years: 10.6–15.6

 > 65 years: 10.9–15.9

 Urine iodine (%)

   

  < 99 µg/L

705 (38.15%)

  

  99–199 µg/L

623 (33.71%)

  

  > 199 µg/L

520 (28.14%)

  

Thyroid function

 FT3, pg/mL

3.29 ± 0.62

2.5–3.9

2.5–3.9

 FT4, pmol/L

10.36 ± 2.15

7.74–20.64

7.74–20.64

 TSH, uiu/mL

1.20 ± 3.02

0.34–5.60

0.34–5.60

 TFQI

0.02 ± 0.33

  

 TSHI

1.84 ± 0.66

  

 TT4RI

19.96 ± 20.88

  

 FT3/FT4

0.51 ± 0.21

  

 SPINA-GT, pmol/s

3.74 ± 50.26

  

 SPINA-GD, nmol/s

46.72 ± 18.94

  

 TgAb, iu/mL

11.47 ± 111.79

0–4.0

0–4.0

 TPOAb, iu/mL

18.85 ± 87.51

0–9.0

0–9.0

 Thyroid autoimmunity (%)

   

  No

1623 (87.82%)

  

  Yes

225 (12.18%)

  
  1. NHANES, National Health and Nutrition Examination Survey; TyG, Triglyceride-glucose; PIR, poverty-to-income ratio; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; CVD, cardiovascular diseases; MetS, metabolic syndrome; PA, physical activity; FBI, fasting blood insulin; HbA1c, glycohemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BUN, blood urea nitrogen; HDL, high density lipoprotein; LDL, low density lipoprotein; TC, total cholesterol; FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid-stimulating hormone; TgAb, anti-thyroglobulin antibody; TPOAb, anti-thyroperoxidase antibody; TSHI, thyrotropin index; TT4RI, thyrotropin thyroxine resistance index; TFQI, thyroid feedback quantile-based index