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Table 4 Comparison of baseline characteristics in patients with HT after IVT

From: Prediction factors and clinical significance of different types of hemorrhagic transformation after intravenous thrombolysis

Variables

mRS 0–2 (342)

mRS 3–6 (639)

p Value

Age (year)

73 (64–79)

80 (72–85)

 < 0.001

Male, %

222 (64.9)

346 (54.1)

0.001

Medical history

 Hypertension, %

224 (65.5)

439 (68.7)

0.317

 Diabetes mellitus, %

51 (14.9)

106 (16.6)

0.523

 Hypercholesterolemia, %

12 (3.5)

40 (6.3)

0.073

 Atrial fibrillation, %

83 (24.3)

248 (38.8)

 < 0.001

 Previous ischemic stroke, %

28 (8.2)

111 (17.4)

 < 0.001

 Smoking, %

80 (23.4)

115 (18.0)

0.045

Prior drugs use

 Prior antiplatelet use, %

53 (15.5)

133 (20.8)

0.049

 Prior anticoagulant use, %

4 (1.2)

22 (3.4)

0.037

 Prior statin use, %

30 (8.8)

67 (10.5)

0.433

Baseline systolic pressure (mmHg)

156 (140–169)

160 (143–172)

0.026

Baseline diastolic pressure (mmHg)

87 (77–96)

86 (78–95)

0.620

Baseline NIHSS score

6 (3–11)

14 (10–20)

 < 0.001

OTT (min)

115 (110–209)

157 (113–206)

0.570

Remote hemorrhage

116 (33.9)

296 (46.3)

 < 0.001

Fibrinolytic drug

  

0.677

 rt-PA, %

339 (99.1)

630 (98.6)

 

 Urokinase, %

3 (0.9)

9 (1.4)

 

Hemorrhage type

  

 < 0.001

 HI, %

255 (74.6)

286 (44.8)

 

 PH, %

87 (25.4)

353 (55.2)

 
  1. mRS modified Rankin Scale, HI hemorrhagic infarction, PH parenchymal hemorrhage, OTT onset to treatment time, rt-PA recombinant tissue plasminogen activator. Bold text indicates a p-value < 0.05