Fig. 6

Differential gene expression analysis in two groups of sepsis samples with high eosinophil/B.cell.memory ratio vs. low eosinophil/B.cell.memory ratio based on data set GSE65682. A Volcano plot shows the differential gene expression between the two groups. The top ten most significant genes were labeled with their gene names. B Clustering heat map of the 774 differential genes reveals the distinct gene expression pattern between the two groups. The rows represent the differential genes and the columns represent the sepsis samples. C Cluster dendrogram shows the partition of 6492 genes into 21 gene modules with different colors. The color bar indicates the assignment of genes to a module. D Bar plot showing the functional enrichment result of the 9 identified modules. These modules with mapped DEGs are M1, M3, M6, M8, M9, M13, M14, M19, and M26