Fig. 4

Esketamine treatment reduced the migration and invasion capabilities of esophageal squamous carcinoma cells (ESCC). Transwell invasion assay was implemented to examine the invasive ability of the KYSE-30 cells and KYSE-150 cells (A). Wound healing assays were conducted to detect the migratory of KYSE-30 cells (B) and KYSE-30cells (C). The migratory ratio was calculated by dividing the wound area by total area. Data are presented as mean ± SEM; **P < 0.01, ***P < 0.001 vs the control group