Fig. 6

Further analysis of key proteins and western blot verification. A Histogram showed actual expression of ERCC6L, AHR, KIF2C, KNTC1 and BCAT1 in our proteomic data of KYSE30 cell after esketamine treatment. B Protein–protein interaction network for these key proteins from STRING database. C Expression levels of ERCC6L, AHR, KIF2C, KNTC1 and BCAT1 in the ESCA tissues and normal tissues from TCGA–ESCA data sets. Western blot analysis of ERCC6L, AHR, KIF2C, KNTC1 and BCAT1 in KYSE30 (D) and KYSE150 (E) under esketamine treatment. Data are presented as mean ± SEM; *P < 0.05, **P < 0.01, ***P < 0.001 vs the control group