Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19

Table 1 Statistical comparison between patients and control group regarding age, gender, and serum GDF-15 level

		Patients group No. = 72	Control group No. = 72	Test value	P-value	Sig
Age (year)	Median(IQR)	6.0 (2.38–10.63)	7.25 (5–10)	− 1.828‡	0.068	NS
Age (year)	Range	0.17–16	3.25–14	− 1.828‡	0.068	NS
Sex	Males	37 (51.4%)	40 (55.6%)	0.251*	0.616	NS
Sex	Females	35 (48.6%)	32 (44.4%)	0.251*	0.616	NS
Serum GDF-15 level (pg/mL)	Median(IQR)	614.23 (338.67–1109.33)	144.66 (89.53–205.8)	−8.501‡	< 0.001	HS
Serum GDF-15 level (pg/mL)	Range	47.47–2940.2	59.36–272.8	−8.501‡	< 0.001	HS

S significant, NS non significant, IQR Inter quartile range. GDF-15 Growth differentiation factor 15, IQR Interquartile range
^*Chi-square test
^‡Mann–Whitney test
P-value < 0.01: highly significant (HS), ˃0.05: non-significant (NS)

ISSN: 2047-783X