Table 6 Validity (AUC, sensitivity, specificity) for serum GDF-15 level to detect COVID-19 in pediatric patients, detect cardiac affection, and detect clinical severity
Parameter | AUC | P-value | Cut of Point (pg/ml) | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|---|
Serum GDF-15 level to detect COVID-19 | 0.910 | < 0.001 | > 272.8 | 79.17 | 100.0 | 100.0 | 82.8 |
Serum GDF-15 level to detect cardiac affection | 0.958 | < 0.001 | > 873.16 | 92.31 | 95.74 | 92.3 | 95.7 |
Serum GDF-15 level to detect clinical severity | 0.957 | < 0.001 | > 688.5 | 88.57 | 97.30 | 96.9 | 90.0 |