Serum growth differentiation factor-15 (GDF-15) is a biomarker of cardiac manifestations in children with COVID-19

Table 7 Multivariate linear regression analysis for predictors of serum GDF-15 level

	Unstandardized Coefficients		Standardized Coefficients	t	P-value
	B	SE	Beta	t	P-value
Weight for age Z-Score	− 35.024	58.018	− 0.060	− 0.604	0.548
Oxygen saturation (Room air)	− 4.141	19.205	− 0.021	− 0.216	0.830
Lymphocytes	− 3.638	19.975	− 0.017	− 0.182	0.856
Platelets	− 0.104	0.465	− 0.021	− 0.224	0.824
ESR	− 1.781	2.303	− 0.086	− 0.774	0.442
CRP	0.551	0.970	0.068	0.568	0.572
LDH	− 0.201	0.294	− 0.081	− 0.683	0.498
D-dimer	11.199	21.072	0.066	0.531	0.597
INR	431.613	149.510	0.273	2.887	0.005
AST	0.713	0.442	0.150	1.614	0.112
CK-MB	− 0.872	1.608	− 0.051	− 0.542	0.590
Troponin I	185.353	329.763	0.065	0.562	0.576
Number of lobes Affected	86.402	48.551	0.195	1.780	0.080
Ejection Fraction	− 31.598	9.301	− 0.465	− 3.397	0.001

ESR Erythrocyte sedimentation rate, CRP C-reactive protein, INR The international normalized ratio, AST aspartate aminotransferase, CK-MB Creatine kinase MB

ISSN: 2047-783X