Table 1 Characteristics of the included studies
Study | Mean age | Sample size (male/female) | Intervention details | Targeted brain region | Period (week) | Number of sessions | Frequency | Duration of sessions | Outcome |
|---|---|---|---|---|---|---|---|---|---|
Bai et al. (2020) | 45.3 ± 6.8 | 30 (13/17) | 1 Hz, 80% RMT, 1000 pulses/session | RIFG | 4 | 20/40 | 5/week | 20 min | AQ |
Barwood et al. (2013) | rTMS: 60.8 ± 6 CON: 67 ± 13.1 | rTMS: 6(4/2) CON: 6(5/1) | 1 Hz, 90% RMT, 1200 pulses/session | RIFG | 2 | 10 | 5/week | 20 min | BDAE |
Chen et al. (2012) | rTMS: 62.9 ± 12.1 CON: 65.1 ± 10.9 | rTMS: 22(12/10) CON: 21(11/10) | 0.5 Hz, 80% RMT, 600 pulses/session | RIFG | 4 | 20 | 5/week | NA | AQ |
Fu et al. (2016) | rTMS: 59.77 ± 5.4 CON: 61.47 ± 6.0 | rTMS: 24(14/10) CON: 24(12/12) | 1 Hz, 90% RMT, 1200 pulses/session | RIFG | 8 | 40 | 5/week | 20 min | CRRCAE |
Haghighi et al. (2017) | rTMS: 61.7 ± 7.1 CON: 60.5 ± 11.9 | rTMS: 6(3/3) CON: 6(2/4) | 1 Hz, 100% RMT, 1000 pulses/session | RIFG | 2 | 10 | 5/week | 30 min | AQ |
Heiss et al. (2013) | rTMS: 68.5 ± 8.2 CON: 69.0 ± 6.3 | rTMS: 17 CON: 14 | 1 Hz, 90% RMT, 800 pulses/session | RIFG | 3–4 | 10 | NA | 20 min | AAT |
Heiss et al. (2013) | rTMS: 61.0 ± 9.8 CON: 57.4 ± 9.6 | rTMS: 19(8/11) CON: 10(5/5) | R: 1 Hz; L: 20 Hz; 80%-110% RMT, 1000 pulses/session | DIFG | 2 | 10 | 5/week | NA | ASRS |
Li et al. (2018) | rTMS: 65.3 ± 5.6 CON: 68.3 ± 5.8 | rTMS: 15(9/6) CON: 15(7/8) | 1 Hz, 80% RMT, 1200 pulses/session | RIFG | 3 | 15 | 5/week | 20 min | WAB |
Ren et al. (2019) | rTMSw: 65.95 ± 8.5 rTMSb: 62.46 ± 10.9 CON: 63.6 ± 16.7 | rTMS-w: 18(7/6) rTMS-b: 13(9/6) CON: 15(9/6) | 1 Hz, 80% RMT, 1200 pulses/session | RIFG | 3 | 15 | 5/week | 20 min | AQ |
Rubi-Fessen et al. (2015) | rTMS: 67.9 ± 8.1 CON: 69.6 ± 6.6 | rTMS: 15(10/5) CON: 15(6/9) | 1 Hz, 90% RMT, 800 pulses/session | RIFG | 2 | 10 | 5/week | 20 min | AAT |
Seniów et al. (2013) | rTMS: 61.8 ± 11.8 CON: 59.7 ± 10.7 | rTMS: 20(8/12) CON: 20(10/10) | 1 Hz, 80% RMT, 1800 pulses/session | RIFG | 3 | 15 | 5/week | 30 min | BDAE |
Shen et al. (2016) | rTMS: 60.2 ± 10.5 CON: 57.5 ± 11.9 | rTMS: 20(11/9) CON: 20(8/12) | 0.5 Hz, 90% RMT, 384 pulses/session | RIFG | 3 | 15 | 5/week | NA | AQ |
Thiel et al. (2013) | rTMS: 69.8 ± 8 CON: 71.2 ± 7.8 | rTMS: 13 CON: 11 | 1 Hz, 90% RMT, 800 pulses/session | RIFG | 2 | 10 | 5/week | 20 min | AAT |
Tsai et al. (2014) | rTMS: 62.3 ± 12.1 CON: 62.8 ± 14.8 | rTMS: 33(24/9) CON: 23(17/6) | 1 Hz, 90% RMT, 600 pulses/session | RIFG | 2 | 10 | 5/week | 10 min | CCAT |
Waldowski et al. (2012) | rTMS: 62.3 ± 11 CON: 60.2 ± 10.6 | rTMS: 13(6/7) CON: 13(7/6) | 1 Hz, 90% RMT, 800 pulses/session | RIFG | 3 | 15 | 5/week | 30 min | BDAE-ASRS |
Wang et al. (2014) | rTMS: 61.7 ± 13.8 CON: 60.4 ± 11.9 | rTMS: 30(27/3) CON: 15(13/2) | 1 Hz, 90% RMT, 1200 pulses/session | RIFG | 2 | 10 | 5/week | 20 min | CCAT |
Weiduschat et al. (2011) | rTMS: 66.7 ± 9.1 CON: 63.8 ± 4.4 | rTMS: 6(1/5) CON: 4(4/0) | 1 Hz, 90% RMT, 1200 pulses/session | RIFG | 2 | 10 | 5/week | 20 min | AAT |
Yoon et al. (2015) | rTMS: 60.5 ± 9.6 CON: 61.1 ± 8.7 | rTMS: 10(8/2) CON: 10(7/3) | 1 Hz, 90% RMT, 1200 pulses/session | RIFG | 4 | 20 | 5/week | 20 min | AQ |