Fig. 9

High expression of SLC10A3 predicts poor prognosis in CRC patients. A IHC analysis of SLC10A3 expression in a CRC patient tissue array (n = 72). SLC10A3 levels in cancer tissues and corresponding normal tissues. Representative images are shown. Scale bars = 100 μm. B IHC scores of SLC10A3 in human CRC tissues and adjacent tissues. C The percent of high and low SLC10A3 expression in CRC patients (normal and cancer tissues). D ROC curve with corresponding AUC value for SLC10A3 when classifying cancer from the mucosa. E–F SLC10A3 expression was positively associated with tumor relapse (R) and metastasis (M). G–H High SLC10A3 expression predicted low OS (HR = 2.23, p-value = 0.022) and DFS (HR = 2.24, p-value = 0.026). Data were shown as mean and standard deviation from three independent experiments. Data are means ± SDs. *, p-value < 0.05; **, p-value < 0.01; ***, p-value < 0.001. CRC colorectal cancer