Table 2 Laboratory and imaging findings of study participants
|  | Control (N = 328) | Case (N = 66) | P-value |
|---|---|---|---|
Laboratory results, median (Q1, Q3) | |||
 Venous BG (mmol/L) | 5.17 (4.65, 6.04) | 6.70 (5.78, 7.62) |  < 0.001 |
 WBC (× 10^9/L) | 6.35 (5.18, 7.45) | 10.7 (8.49, 12.6) |  < 0.001 |
 N (%), mean ± SD | 65.7 (± 9.60) | 81.4 (± 9.37) |  < 0.001 |
 RDW-CV (%) | 13.0 (12.3, 13.6) | 13.0 (12.4, 13.7) | 0.755 |
 Serum K+ (mmol/L) | 3.96 (3.71, 4.27) | 3.92 (3.60, 4.25) | 0.875 |
 TBIL (μmol/L) | 10.3 (7.48, 13.5) | 12.3 (8.65, 17.1) | 0.006 |
 DBIL (μmol/L) | 3.20 (2.30, 4.20) | 4.10 (3.40, 5.60) |  < 0.001 |
 Scr (μmol/L) | 86.6 (66.4, 148) | 93.5 (74.0, 119) | 0.996 |
 CK-MB (μg/L) | 14.7 (12.3, 17.8) | 13.0 (8.23, 20.6) | 0.435 |
 NT-proBNP (pg/mL) | 159 (53.9, 1000) | 181 (102, 660) | 0.953 |
 Triglyceride (mmol/L) | 1.66 (1.20, 2.43) | 1.27 (1.01, 2.06) | 0.035 |
 Total cholesterol (mmol/L) | 4.39 (3.69, 5.01) | 3.99 (3.62, 4.74) | 0.124 |
 HDL-C (mmol/L) | 1.05 (0.868, 1.24) | 1.00 (0.863, 1.17) | 0.707 |
 LDL-C (mmol/L) | 2.71 (2.12, 3.31) | 2.34 (1.88, 2.96) | 0.012 |
 PT (s) | 12.4 (11.2, 13.2) | 13.2 (12.2, 14.0) |  < 0.001 |
 APTT (s) | 33.9 (28.1, 37.4) | 35.0 (28.1, 38.0) | 0.69 |
 D-Dimer (μg/mL) | 0.30 (0.20, 0.52) | 2.32 (1.40, 4.43) |  < 0.001 |
 FDP (μg/mL) | 1.92 (1.41, 2.39) | 10.3 (5.19, 25.0) |  < 0.001 |
 PRC (pg/mL) | 10.2 (4.72, 23.6) | 7.42 (3.24, 18.7) | 0.351 |
 Ang-II (ng/dL) | 12.3 (9.90, 14.4) | 11.0 (8.34, 13.9) | 0.010 |
 PAC (ng/dL) | 16.2 (11.7, 23.9) | 18.8 (15.5, 28.0) | 0.005 |
Imaging examination results | Â | Â | Â |
 Aortic diameter (mm), Median (Q1, Q3) | 30.0 (28.0, 33.0) | 35.0 (30.0, 42.0) |  < 0.001 |
 Aortic regurgitation (n, %) | 117 (35.7%) | 32 (48.5%) | 0.147 |
 Ejection fraction (%), Median (Q1, Q3) | 62.0 (60.0, 64.0) | 62.0 (60.0, 66.8) | 0.357 |