Higher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study

Table 4 Univariate analysis in laboratory and imaging findings for prevalence of aortic diseases

	OR (95% CI)	P-value
Laboratory results
Venous blood glucose (mmol/L)	1.697(1.441–2.023)	< 0.001
WBC (× 10^9/L)	2.144 (1.817–2.597)	< 0.001
N (%)	1.205 (1.157–1.261)	< 0.001
RDW-CV (%)	1.082 (0.873–1.318)	0.447
Serum K⁺ (mmol/L)	0.957 (0.553–1.629)	0.872
Total bilirubin (μmol/L)	1.101 (1.050–1.158)	< 0.001
Direct bilirubin (μmol/L)	1.379 (1.206–1.584)	< 0.001
Serum creatinine (μmol/L)	0.996 (0.993–0.999)	0.019
CK-MB (μg/L)	0.965 (0.917–1.016)	0.892
NT-proBNP (pg/mL)	1.000 (1.000–1.000)	0.196
Triglyceride (mmol/L)	0.821 (0.641–1.015)	0.090
Total cholesterol (mmol/L)	0.767 (0.591–0.988)	0.044
HDL-C (mmol/L)	0.629 (0.247–1.516)	0.316
LDL-C (mmol/L)	0.625 (0.458–0.842)	0.002
PT (s)	1.546 (1.281–1.888)	< 0.001
APTT (s)	1.021 (0.980–1.064)	0.314
D-Dimer (μg/mL)	8.717 (5.403–15.140)	< 0.001
FDP (μg/mL)	2.171 (1.804–2.700)	< 0.001
PRC (pg/mL)	0.995 (0.983–1.005)	0.392
Ang-II (ng/dL)	0.990 (0.982–0.997)	0.012
PAC (ng/dL)	1.030 (1.007–1.051)	0.009
Imaging examination results
Aortic diameter (mm)	1.697 (0.994–2.896)	< 0.001
Aortic regurgitation	2.375 (1.040–5.425)	0.052
Ejection fraction (%)	1.005 (0.960–1.055)	0.84
Ejection fraction (%)	1.005 (0.960–1.055)	0.84

WBC indicates white blood cell; N neutrophil, RDW-CV coefficient of variation of red blood cell distribution width, serum K⁺, serum potassium concentration; CK-MB creatine kinase isoenzyme MB, NT-proBNP N-terminal pro-brain natriuretic peptide, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, PT prothrombin time, APTT activated partial thromboplastin time, FDP fibrin degradation products, PRC plasma renin concentration, Ang-II angiotensin II; PAC, plasma aldosterone concentration

ISSN: 2047-783X