| Â | Unadjusted model | Model 1 | Model 2 |
|---|
OR (95%CI) | P-value | OR (95%CI) | P-value | OR (95%CI) | P-value |
|---|
PAC, ng/dL | 1.030 (1.007–1.053) | 0.009 | 1.033 (1.009–1.056) | 0.006 | 1.138 (1.062–1.238) |  < 0.001 |
PAC per 3 ng/dL | 1.093 (1.021–1.168) | 0.009 | 1.101 (1.027–1.179) | 0.006 | 1.475 (1.198–1.898) |  < 0.001 |
PAC per 5 ng/dL | 1.160 (1.035–1.296) | 0.009 | 1.174 (1.046–1.315) | 0.006 | 1.912 (1.351–2.910) |  < 0.001 |
PAC per 7 ng/dL | 1.230 (1.050–1.437) | 0.009 | 1.251 (1.065–1.467) | 0.006 | 2.477 (1.524–4.460) |  < 0.001 |
PAC median | Â | Â | Â | Â | Â | Â |
 <16.58 ng/dL | 1 |  | 1 |  | 1 |  |
 ≥16.58 ng/dL | 2.112 (1.229–3.714) | 0.008 | 2.224 (1.282–3.947) | 0.005 | 8.230 (1.728–54.074) | 0.015 |
- Model 1 was adjusted for age, gender. Model 2 was adjusted for gender, BMI, smoking, duration of hypertension, grade 3 hypertension, diabetes, stroke, CHD, CKD, adrenal lesion, family medical history, medication history of ACEI and ARB, heart rates, SBP, DBP, HR, VBG, WBC, N%, RDW-CV, K+, TBIL, CK-MB, NT-proBNP, TG, LDL-C, APTT, PRC, Ang-II, PAC, aortic diameter, aortic regurgitation and ejection fraction. BMI, body mass index; CHD, coronary heart disease, CKD, chronic kidney disease; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rates; VBG, venous blood glucose; WBC, white blood cell; N, neutrophil; RDW-CV, coefficient of variation of red blood cell distribution width; K+, serum potassium concentration; TBIL, total bilirubin; CK-MB, creatine kinase isoenzyme MB, NT-proBNP, N-terminal pro-brain natriuretic peptide; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; APTT, activated partial thromboplastin time; PRC, plasma renin concentration, Ang-II, angiotensin II; PAC, plasma aldosterone concentration
